Study of the Prevalence of Hyperandrogenemia in Greek Women with Polycystic Ovary Syndrome Based on Two Different Diagnostic Criteria (NIH 1990, Rotterdam 2004)
July 2017
hyperandrogenemia polycystic ovary syndrome PCOS NIH 1990 Rotterdam 2004 endocrine disorder clinical hyperandrogenism biochemical hyperandrogenism ovarian dysfunction polycystic ovaries hirsutism acne oily skin alopecia menstrual disturbances infertility testosterone Δ4-androstenedione dehydroepiandrosterone NIH criteria Rotterdam criteria androgen excess hair loss skin oiliness irregular periods
TLDR Accurate diagnosis of PCOS requires comprehensive androgen measurement.
The study investigated the prevalence of hyperandrogenemia in Greek women with polycystic ovary syndrome (PCOS) using two diagnostic criteria: NIH 1990 and Rotterdam 2004. PCOS was identified as a significant endocrine disorder affecting 5%-9% of women of reproductive age. Key diagnostic features included clinical or biochemical hyperandrogenism, ovarian dysfunction, and polycystic ovaries. Hyperandrogenemia, characterized by symptoms such as hirsutism, acne, oily skin, alopecia, menstrual disturbances, and infertility, was a major diagnostic criterion. Testosterone, Δ4-androstenedione, and dehydroepiandrosterone were the primary androgens associated with PCOS. The study highlighted the importance of comprehensive androgen measurement for accurate diagnosis.
