A Systematic Review of the Effectiveness of Probiotics in the Treatment of Acne Vulgaris Since 2020: A Quantitative Study
November 2025
in “
Research Review
”
TLDR Probiotics can help reduce acne and improve skin health.
This systematic review evaluates the effectiveness of probiotics in treating acne vulgaris, analyzing 5 studies with 310 participants. The findings indicate that probiotics significantly reduce acne lesions, improve skin hydration, and enhance overall skin health, with low incidence of mild adverse effects. Probiotics were found to inhibit Propionibacterium acnes, modulate immune responses, and repair the skin barrier. Despite promising results, the review highlights limitations such as small sample sizes and potential biases, emphasizing the need for larger, high-quality studies to confirm these findings and optimize treatment protocols. Probiotics may serve as an adjunctive or alternative therapy for acne, especially for those experiencing side effects from conventional treatments.