Harnessing Regenerative Science in Aesthetic Surgery: The Biologically Driven Future

    September 2025 in “ Journal of Clinical Medicine ”
    Claire Olivas, Orr Shauly, Dana M. Hutchison, Daniel J. Gould
    TLDR Regenerative medicine could revolutionize aesthetic surgery, but needs careful validation and ethical use.
    This narrative review discusses the transformative potential of regenerative medicine in aesthetic and reconstructive surgery, focusing on biologic therapies like exosomes, PRP, and ASCs. It highlights their mechanisms, clinical efficacy, and regulatory issues, and explores synergistic strategies with laser technologies. Future developments in mitochondrial and microRNA-based therapies, synthetic exosome mimetics, and AI-assisted biologic design are also examined. The review emphasizes the need for rigorous validation, ethical responsibility, and a patient-centered approach to integrate these innovations safely and accessibly into mainstream practice.
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