May 2026 in “Frontiers in Cell and Developmental Biology” This review discusses the potential of mesenchymal stem cells (MSCs) and their extracellular vesicles (EVs) as a cell-free therapy for burn management, focusing on their roles in inflammation regulation, angiogenesis, epithelial regeneration, and ECM remodeling. The authors propose a framework for translating these therapies into clinical practice, highlighting their advantages in addressing inflammation, regeneration, and fibrosis. However, challenges such as donor consistency, GMP compliance, standardization of quality attributes, and optimization of administration strategies need to be addressed. The review emphasizes the importance of establishing standardized production and quality-control systems and conducting multicenter randomized studies to facilitate the translation of MSC/EV therapies from research to clinical application.
Correcting EDA fibronectin organization and YAP translocation can improve wound healing in fibrotic conditions.
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April 2009 in “Journal of the American College of Certified Wound Specialists” Bidirectional barbed sutures are effective and can reduce surgery time, with a low infection rate and potential cost savings despite being more expensive.
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May 2016 in “Aging Cell” Older people's sweat glands are less effective at helping skin wounds heal due to weaker cell connections.
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February 2017 in “Archives of Aesthetic Plastic Surgery” Double-layer scalp wound closure is better than single-layer closure after strip hair transplant surgery.