TLDR Umbilical cord cells may help delay skin aging.
This review discusses the potential of umbilical cord-derived mesenchymal stromal cells (UC-MSCs) in skin rejuvenation, highlighting their ability to delay skin aging. Skin aging, characterized by decreased collagen and elastin synthesis, increased wrinkles, and pigmentation, is influenced by both internal and external factors. UC-MSCs, identified as pluripotent progenitor cells with self-renewal and differentiation capabilities, offer promising therapeutic avenues. The paper emphasizes the importance of understanding the mechanisms of UC-MSCs in combating skin aging to facilitate their clinical application and provides a comprehensive overview of recent findings in this area.
263 citations
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February 2020 in “International journal of molecular sciences” ADSCs help in wound healing and skin regeneration but need more research for full understanding.
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April 2021 in “Frontiers in Cell and Developmental Biology” MSC-derived exosomes may help in skin repair and regeneration.
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December 2021 in “Stem Cell Research & Therapy” MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.
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June 2022 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.