Shrimp-Derived Extracts as Antibacterial, Antioxidant, and Burn Wound-Healing Agents: Comprehensive In Vitro and In Vivo Evaluation from Yemeni Coastal Resources

The study explores the potential of shrimp-derived extracts, particularly chitosan, as antibacterial, antioxidant, and burn wound-healing agents. The extracts showed significant antibacterial activity against pathogens like Staphylococcus aureus and Escherichia coli, and antioxidant properties were confirmed using the DPPH assay. In rat models, a chitosan-based ointment demonstrated promising results in accelerating burn wound healing by promoting collagen synthesis and reducing inflammation. However, the study's small sample size (n=2 per group) limits the statistical significance of the findings, indicating the need for larger studies to confirm these results. The research highlights the potential of utilizing shrimp extracts from Yemeni coastal resources in developing therapeutic agents, especially in regions with limited access to advanced medical treatments.