Title
October 2001
in “
Journal of the American Academy of Dermatology
”
TLDR Topical minoxidil and anthralin work for patchy alopecia areata but not for alopecia totalis/universalis.
The document discussed the challenges in evaluating treatments for alopecia areata (AA), particularly the need to distinguish between alopecia totalis/universalis (AT/AU) and patchy AA due to their differing prognoses and treatment responses. It highlighted that while topical minoxidil and anthralin showed efficacy in treating patchy AA, they were ineffective for AT/AU. The author emphasized the importance of segregating patient groups in studies to avoid skewed results and acknowledged that previous studies often included a high proportion of AT/AU cases, which could misrepresent treatment efficacy. The document also noted that irritation is not necessary for anthralin's effectiveness, countering some previous assumptions.