Title

    Jerry Shapiro
    TLDR Topical minoxidil and anthralin work for patchy alopecia areata but not for alopecia totalis/universalis.
    The document discussed the challenges in evaluating treatments for alopecia areata (AA), particularly the need to distinguish between alopecia totalis/universalis (AT/AU) and patchy AA due to their differing prognoses and treatment responses. It highlighted that while topical minoxidil and anthralin showed efficacy in treating patchy AA, they were ineffective for AT/AU. The author emphasized the importance of segregating patient groups in studies to avoid skewed results and acknowledged that previous studies often included a high proportion of AT/AU cases, which could misrepresent treatment efficacy. The document also noted that irritation is not necessary for anthralin's effectiveness, countering some previous assumptions.
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