Progress of Ursolic Acid on the Regulation of Macrophage: Summary and Prospect

    May 2025 in “ Frontiers in Immunology
    Wenjing Feng, Kun Yang, Ying Zou, Zhengguo Xiao, Rongkang Qian, Ronghua Qian, Ronghua Qian, Ronghua Qian
    TLDR Ursolic acid may help develop new anti-inflammatory drugs by affecting immune cells.
    Ursolic acid (UA) is highlighted for its significant role in anti-inflammatory processes and immune regulation, particularly through its effects on macrophages, which are key in immune responses. The paper discusses UA's regulatory effects on macrophage function and its therapeutic potential across various diseases. It suggests that UA's ability to modulate different types of macrophages could inspire new anti-inflammatory and immunomodulatory drug developments. However, further research is needed to fully understand UA's mechanisms in macrophages and its clinical applications.
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