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Glossary5-Fluorouracil

chemotherapy drug that inhibits cancer cell DNA synthesis

5-Fluorouracil (5-FU) is a chemotherapy medication used to treat various types of cancer, including colon, breast, and skin cancers. It works by interfering with the DNA and RNA synthesis of cancer cells, preventing them from growing and dividing.

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Research

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Docetaxel, Cisplatin and 5-Fluorouracil in Patients with Locally Advanced Unresectable Head and Neck Cancer: A Phase I-II Feasibility Study

research Docetaxel, cisplatin and 5-fluorouracil in patients with locally advanced unresectable head and neck cancer: a phase I–II feasibility study

78 citations , March 2004 in “Annals of Oncology”

The treatment combining docetaxel, cisplatin, and 5-FU is feasible and effective for advanced head and neck cancer.

research The efficacy of adding topical 5‐fluorouracil to micro‐needling in the treatment of vitiligo: A randomized controlled trial

16 citations , January 2023 in “Journal of Cosmetic Dermatology”

Micro-needling with 5-FU is more effective for vitiligo than tacrolimus alone.

research Corticosteroid Atrophy Plaque on the Scalp Treated with 5-Fluourouracil and Bleomycin Infusion in the MMP Technique

1 citations , May 2024 in “Skin Appendage Disorders”

Hair regrowth was achieved using 5-Fluorouracil and Bleomycin for scalp atrophy caused by corticosteroids.

Phenytoin or Spironolactone Intervention Counteracts 5-Fluorouracil-Induced Alopecia in Rats by Suppressing Oxidative Stress and Inflammation While Promoting Collagen Synthesis

research Phenytoin or Spironolactone Intervention Counteracts 5-Fluorouracil–Induced Alopecia in Rats by Suppressing Oxidative Stress and Inflammation While Promoting Collagen Synthesis

November 2025 in “Preprints.org”

Phenytoin and spironolactone help prevent hair loss from chemotherapy by reducing stress and inflammation.

research Comparison of intralesional triamcinolone acetonide alone and with 5 -fluorouracil for the treatment of keloids

July 2025 in “Journal of the Pakistan Medical Association”

Combining TCA with 5-FU is more effective and safer for treating keloids than TCA alone.

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community 5 Months on RU58841: Thin Front Area and Hair Loss Rate

in Basic Questions 53 upvotes 1 month ago

The conversation discusses using RU58841 for hair loss, with OP experiencing thinning in the front area and steady hair loss. OP plans to try microneedling while avoiding finasteride and dutasteride.

community 5.5 months on topical fin and 1ye on oral min (9mon 1.25 and last 3mon on 2.5) and no results.

in Update 30 upvotes 2 months ago

The user has been using topical finasteride and oral minoxidil for hair loss but has seen no results after 5.5 months and 1 year, respectively. Many commenters suggest the user's hair looks good, recommend continuing treatment for maintenance, and discuss potential side effects and alternative treatments.

community 5 MONTHS DUT RESULTS (24M) what can i do to improve it?

in Is this regrowth? 7 upvotes 2 months ago

A 24-year-old male has been using oral Minoxidil (2.5mg daily) and daily Dutasteride for hair loss, noticing slight thickening but no major regrowth. Users suggest increasing Minoxidil dosage to 5mg and maintaining consistency, with some recommending additional treatments like topical Minoxidil or considering a hair transplant in the future.

community 5 Months on Dutasteride 0.5 Minoxidil Topical 5%

in Progress Pictures 41 upvotes 2 months ago

The conversation discusses hair loss treatment progress using Dutasteride 0.5 and topical Minoxidil 5%. Users inquire about side effects and previous use of Finasteride.

community 5 months of 1 mg finasteride EOD and minoxidil

in Is this regrowth? 35 upvotes 2 months ago

The user has been using finasteride every other day and oral minoxidil for hair regrowth, noticing new baby hairs. They are hopeful about regaining hair on their temples.

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