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GlossaryAlkaline Phosphatase Activity

enzyme function indicating liver or bone health

Alkaline Phosphatase Activity (ALP Activity) refers to the function of the enzyme alkaline phosphatase, which is found in various tissues throughout the body, including the liver, bones, kidneys, and digestive system. This enzyme plays a crucial role in breaking down proteins and is often measured in blood tests to assess liver function, bone health, and to diagnose certain medical conditions. Elevated or decreased levels of ALP can indicate issues such as liver disease, bone disorders, or other health problems.

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Research

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research Proteomics demonstration that histone H4 is a colchicine-induced retro-modulator of growth and alkaline phosphatase activity in hair follicle dermal papilla culture

5 citations , March 2011 in “Journal of proteomics”

Histone H4, released by cells exposed to colchicine, can cause hair loss by inhibiting cell growth and enzyme activity.

research Alkaline Phosphatase in Alopecia Areata

23 citations , September 1957 in “Archives of Dermatology”

Alkaline phosphatase activity decreases in early alopecia areata.

Dermal Papilla Cells Serially Cultured with Wnt-10b Sustain Their Hair Follicle Induction Activity After Transplantation into Nude Mice

research Dermal Papilla Cells Serially Cultured with Wnt-10b Sustain their Hair Follicle Induction Activity after Transplantation into Nude Mice

22 citations , October 2012 in “Cell Transplantation”

Cells treated with Wnt-10b can grow hair after being transplanted into mice.

research Alkaline Phosphatase Reaction in Hair Follicles of Male Beagle Dogs during Hair Cycle Stages*

2 citations , September 1978 in “Anatomia Histologia Embryologia”

Alkaline phosphatase activity in Beagle dog hair follicles is weakest in anagen and strongest in telogen.

research Hair Growth–Promoting Activity of Flavone-Rich Fractions Derived from Eremochloa ophiuroides extracts

March 2026 in “The Korean Society for Veterinary Nursing”

Eremochloa ophiuroides extracts may effectively promote hair growth like minoxidil.

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Community Join

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

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Learn

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learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

learn KY19382

compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

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