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highly targeted anti-androgen that might have minimal systemic effects
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research Minoxidil May Suppress Androgen Receptor-Related Functions
Minoxidil can reduce functions related to androgen receptors.
research Stem Cell-Derived Motor Neurons from Spinal and Bulbar Muscular Atrophy Patients
The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.
research Modeling Androgen Synthesis and Action During Human Sexual Differentiation
Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
research Histological and Immunohistochemical Examination of the Effect of the Nonsteroidal Antiandrogen Flutamide on Some Organs of the Male Reproductive System in Albino Rats
Flutamide caused damage to male rat reproductive organs and may affect fertility.
research The Evolutionary Impact of Androgen Levels on Prostate Cancer in a Multi-Scale Mathematical Model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
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5 / 598 resultscommunity Minoxidil is a 5ar inhibitor according to research
Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.
community Research: Minoxidil grows hair by suppressing androgen activity (DHT) in hair follicles.
Minoxidil may suppress androgen activity in hair follicles, potentially aiding in hair growth and prostate cancer treatment. Users discuss the effectiveness of minoxidil and finasteride for hair maintenance and regrowth, with some preferring topical applications over oral due to safety concerns.
community Concerns about CosmeRNA safety mechanisms
Concerns about CosmeRNA safety mechanisms and potential side effects. Discussion includes comparisons to Fluridil and questions about nanoparticle specificity and siRNA stability.
community Hair was retained after stopping finasteride, a decade later. Anyone else?
After stopping finasteride, the user retained hair without noticeable balding, suggesting an unusual reaction to the medication. The user initially experienced rapid hair loss and itchiness, possibly due to male pattern baldness, but maintained hair stability after tapering off finasteride.
community Since there is so much hype for cosmeRNA and HMI-115...
Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.