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Efficacy and Safety of Autologous Cell-Based Therapies for Atrophic Acne Scar Treatment: An Updated Systematic Review and Meta-Analysis with In-Depth Methodological and Clinical Insights

research Efficacy and safety of autologous cell-based therapies for atrophic acne scar treatment: an updated systematic review and meta-analysis with in-depth methodological and clinical insights

March 2026 in “Frontiers in Cell and Developmental Biology”

Autologous cell-based therapies, especially SVF, effectively and safely improve atrophic acne scars.

Comparison of 1064-nm Nd:YAG Picosecond Lasers Using Fractional Micro-Lens Array vs. Ablative Fractional 2940-nm Er:YAG Lasers for the Treatment of Atrophic Acne Scar in Asians: A 20-Week Prospective, Randomized, Split-Face, Controlled Trial

research 604 Comparison of 1064-nm Nd:YAG picosecond lasers using fractional micro-lens array vs. ablative fractional 2940-nm Er:YAG lasers for the treatment of atrophic acne scar in Asians: A 20-week prospective, randomized, split-face, controlled trial

April 2023 in “Journal of Investigative Dermatology”

Both laser treatments improved acne scars similarly, but the Nd:YAG laser was safer and less painful, while the Er:YAG laser left patients slightly more satisfied.

research Synergistic Effects of Fractional CO ₂ Laser and Recombinant Humanized Type III Collagen (rhCol III) in Atrophic Acne Scar Treatment: Activation of MAPK Pathway and Enhanced Collagen Remodeling

January 2025 in “Dermatologic Therapy”

Combining fractional CO₂ laser with type III collagen improves acne scar treatment.

Study to Compare the Efficacy of 50% Glycolic Acid with 65% Trichloroacetic Acid in the Treatment of Atrophic Acne Scars by CROSS Technique

research Study to compare the efficacy of 50% glycolic acid with 65% trichloroacetic acid in the treatment of atrophic acne scar by CROSS technique

1 citations , August 2024 in “Journal of Cutaneous and Aesthetic Surgery”

65% TCA improves acne scars more but has more side effects than 50% GA.

research Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars

62 citations , October 2017 in “JAMA facial plastic surgery”

Condensed nanofat with fat grafts effectively improves atrophic facial scars.

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community Anyone here have a lot of knowledge on hair follicle stem cells and progenitor cells for PP405?

in Chat 4 upvotes 7 months ago

Hair follicle stem cells remain in bald individuals, but progenitor cells do not, raising questions about hair regrowth claims by Pelage. PP405 is discussed as a potential treatment, with skepticism about its effectiveness compared to existing treatments like Minoxidil and Finasteride.

community Derminator2 causing scars (microscope images attached)

in Microneedling 61 upvotes 2 years ago

User experienced scarring from microneedling at fast speed and paused treatment for 3-4 weeks to recover. Advice given includes waiting a full month for recovery to avoid scars.

community Seeking Analysis: Receded Temple Closeups for Scarring or AGA Signs

in Basic Questions 35 upvotes 1 month ago

The conversation is about analyzing receded temple closeups for signs of fibrosis, scarring, or androgenetic alopecia (AGA). Specific treatments like Minoxidil, finasteride, or RU58841 are not mentioned in the conversation.

community Starting Treatment for CCCA (scarring alopecia)

in Treatment 6 upvotes 2 years ago

A male in his early 20s with CCCA (scarring alopecia) started treatment with Finasteride, Fluocinolone, and Doxycycline. Steroid injections were suggested but not yet done.

community Tropoelastin injections + verteporfin?

in Research/Science 12 upvotes 3 years ago

The use of tropoelastin injections and verteporfin for hair transplant recipients to help regrow donor area hairs, as well as research done on tropoelastin injections restoring elastin in scarred heart tissue and skin. There are discussions about why it is taking so long to get cosmetic mass produced tropoelastin injectables on the market.

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