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balance between cell survival and cell death proteins

The Bcl-2/Bax ratio refers to the balance between two types of proteins that regulate cell death. Bcl-2 is a protein that prevents cells from dying, while Bax promotes cell death. A higher Bcl-2/Bax ratio means cells are more likely to survive, whereas a lower ratio indicates a higher likelihood of cell death. This balance is crucial in processes like cancer development and treatment, as well as in conditions like alopecia where cell survival and death are key factors.

Related Terms

• Bcl-2 family
• Bax
• B-cell lymphoma 2
• BRCA2
• BMAL1
• MHC Class I Polypeptide-Related Sequence B
• BRCA1
• Caspase-3