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Research
5 / 1000+ resultsresearch Hereditary vitamin D resistant rickets (HVDRR) case series: phenotype, genotype, conventional treatment, and adjunctive cinacalcet therapy
This study examined 8 patients with hereditary vitamin D resistant rickets (HVDRR) from 5 Saudi families, all of whom exhibited alopecia and secondary hyperparathyroidism. Genetic analysis identified 3 distinct mutations in the vitamin D receptor gene. Four patients were treated with high-dose calcium alone, while the other 4 received additional cinacalcet, a calcimimetic. The use of cinacalcet showed promise in improving serum PTH levels without causing hypocalcaemia, suggesting it may be a safe and valuable adjunctive therapy. However, the response to treatment varied, and further research is needed to confirm these findings.
research STUDIES ON A SKIN CALCIFYING SYSTEM
Mild skin injury can trigger mineral deposits in rat skin, even without full calciphylactic response.
research Systemic and Topical Factors Involved in the Production of Experimental Cutaneous Calcinosis11From the Institut de Médecine et de Chirurgie expérimentales, Université de Montréal, Montréal, Canada.
Cutaneous calcinosis can be induced in young animals using certain compounds, but only in specific areas and with high mortality.
research Expression of Calcyclin, a Calcium-Binding Protein, in the Keratogenous Region of Growing Hair Follicles
research Calcipotriol/dithranol
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5 / 1000+ resultscommunity Anyone used Topical Calcipotriol (cream) or VPA ( Valproic Acid)
The conversation discusses using topical Calcipotriol and Valproic Acid for hair loss, focusing on their mechanisms involving the VDR receptor and Wnt/beta-catenin pathway. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.
community Using topical vitamin D, does it make sense?
Topical Calcipotriol (vitamin D derivative) may help with hair regrowth, especially for alopecia areata. The user wonders if adding classic vitamin D to lotions like Minoxidil could have a similar effect.
community REVOLUTION in AUGUST: New possibilities according to Dr. Muñoz (pinacidil, cromakalim, diazoxide and nicorandil)
Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.
community Taking Potassium Chloride and Magnesium made minoxidil-induced palpitations 0
Taking potassium chloride and magnesium stopped minoxidil-induced palpitations. The user is considering continuing minoxidil with these supplements.
community The Effects of the Potassium Channel Opener Minoxidil on Renal Electrolytes Transport in the Loop of Henle
This post and conversation are about the effects of Minoxidil on renal electrolytes transport in the Loop of Henle. The replies show a lack of interest and a brief summary stating that rectal Minoxidil electrolytes are bad.