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GlossaryCircular RNAs

circular RNA molecules form closed loops, enhancing stability

Circular RNAs (circRNAs) are a type of RNA molecule that, unlike the more common linear RNAs, form a covalently closed loop. This unique structure makes them more stable and resistant to degradation. They play various roles in gene regulation, including acting as molecular sponges for microRNAs, and are being studied for their potential involvement in diseases and as therapeutic targets.

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The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis

research The Circular RNA CircCOL1A1 Functions as a miR-149-5p Sponge to Regulate the Formation of Superior-Quality Brush Hair via the CMTM3/AR Axis

3 citations , February 2022 in “Frontiers in cell and developmental biology”

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

Systematic Analysis of Non-coding RNAs Involved in the Angora Rabbit Hair Follicle Cycle by RNA Sequencing

research Systematic Analysis of Non-coding RNAs Involved in the Angora Rabbit (Oryctolagus cuniculus) Hair Follicle Cycle by RNA Sequencing

35 citations , May 2019 in “Frontiers in genetics”

Non-coding RNAs play key roles in the hair growth cycle of Angora rabbits.

research Comprehensive analysis of circRNAs from cashmere goat skin by next generation RNA sequencing (RNA-seq)

39 citations , January 2020 in “Scientific Reports”

Four circRNAs were found to be significantly different in cashmere goat skin, affecting cashmere fineness.

The Roles of Non-Coding RNA in the Development and Regeneration of Hair Follicles: Current Status and Further Perspectives

research The Roles of Non-coding RNA in the Development and Regeneration of Hair Follicles: Current Status and Further Perspectives

11 citations , October 2021 in “Frontiers in Cell and Developmental Biology”

Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.

Novel circRNAs From Cashmere Goats: Discovery, Integrated Regulatory Network, and Their Putative Roles in the Regeneration and Growth of Secondary Hair Follicles

research Novel circRNAs from cashmere goats: Discovery, integrated regulatory network, and their putative roles in the regeneration and growth of secondary hair follicles

7 citations , June 2022 in “Czech Journal of Animal Science”

Certain circular RNAs help cashmere goats grow more hair.

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