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    Did you mean Cyclooxygenase-2?
    GlossaryCyclooxygenase-2

    enzyme involved in inflammation and pain production

    Cyclooxygenase-2 (COX-2) is an enzyme that plays a crucial role in the inflammatory process by converting arachidonic acid into prostaglandins, which are compounds that mediate inflammation and pain. Unlike its counterpart COX-1, which is expressed constantly in most tissues, COX-2 is typically induced during inflammation and is a target for anti-inflammatory drugs like NSAIDs (nonsteroidal anti-inflammatory drugs).

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      community Brotzu lotion update

      in Update  90 upvotes 8 years ago
      A new hair loss lotion by Dr. Brotzu, expected to regrow up to 5 years of lost hair, is set to be released by Fidia Farmaceutici. It claims to work like minoxidil and finasteride without side effects, but skepticism exists due to its classification as a cosmetic product.

      community how to compound topical cyclosporine

      in Treatment  8 upvotes 3 years ago
      The conversation is about compounding topical cyclosporine for hair loss, suggesting it needs an oil base like castor oil. The user seeks tips or tricks for the process.

      community Stemoxydin and hair cycle question

      in Treatment  2 upvotes 2 years ago
      The user has been using Finasteride for hair loss and is considering adding alphatradiol, stemoxydine, or 2% minoxidil to their regimen. They are concerned that stemoxydine, which shortens the resting phase of hair, might accelerate hair loss in those not using Finasteride by depleting hair cycles without strengthening miniaturized hairs.

      community An Uncontrolled Case Series Using a Botanically Derived, β-Cyclodextrin Inclusion Complex in Two Androgenetic Alopecia-Affected Male Subjects

      in Research/Science  1 upvotes 5 years ago
      The conversation discusses a botanically derived treatment for androgenetic alopecia using ingredients like saw palmetto, green tea, and evening primrose, showing impressive results over 270 days. Concerns include the study's uncontrolled nature and potential product motivation, with suggestions to enhance absorption through derma rolling.

      community RU and cetosomal minoxidil topical

      in Minoxidil  1 upvotes 2 months ago
      Mixing RU58841 with cetosomal minoxidil is discussed due to scalp irritation from ethanol PG vehicles. A mixture of the two turned bright pink when left to dry.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2448 upvotes 4 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community Is stemoxydine (serioxyl advanced) toxic/lethal to cats?

      in Chat  1 upvotes 1 year ago
      The conversation is about concerns regarding the safety of using stemoxydine (Serioxyl Advanced) around cats, with the user also using minoxidil, oral minoxidil, dutasteride, and microneedling for hair loss. The user is seeking advice on whether stemoxydine is toxic or lethal to cats.

      community Hyperbaric Oxygen Therapy (HBOT)

      in Research/Science  8 upvotes 4 years ago
      Hyperbaric Oxygen Therapy (HBOT) is discussed as a potential treatment for androgenic alopecia due to its ability to reverse hypoxia and promote angiogenesis. The conversation explores its potential benefits for hair loss, though no studies have been conducted on this application yet.

      community JXL082 is not PP405 and Everychem followed the wrong lead

      in Research/Science  41 upvotes 8 months ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

      community Insane Idea: Cyperus Rotundus Oil?

      in Research/Science  9 upvotes 1 year ago
      Cyperus rotundus oil is suggested as a natural treatment for androgenic alopecia, potentially inhibiting hair growth without affecting testosterone levels. The conversation questions its effectiveness and safety for scalp use.

      community CoQ10 and Fish Oil body hair growth

      in Female  4 upvotes 1 year ago
      Taking CoQ10 and fish oil supplements may lead to increased body hair growth and a crawling sensation on the scalp and skin. The user suspects these supplements could be linked to hair growth, possibly due to their effects on heart health and cholesterol management.

      community Where do you guys get your stemoxydine from?

      in Product  2 upvotes 1 year ago
      Stemoxydine is available in L'Oréal's Serioxyl and Dercos Neogenic products, which can be found on Amazon, Ulta, or L'Oréal's website. A user is selling three bottles of L'Oréal Stemoxydine.

      community Is Stemoxydine a DHT blocker.?

      in Product  2 upvotes 1 year ago
      Stemoxydine is not a DHT blocker; it works independently to stimulate hair growth. Users discussed its function and clarified it does not block DHT.

      community Has anyone tried CB-01-03 aka Clascoterone?

      in Research/Science  2 upvotes 1 month ago
      Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.

      community Anyone knows if koshine kx-826 has propylene glicol?

      in Product 6 months ago
      Koshine KX-826 has different versions, and the green version uses a plant-based carrier that may be less irritating for those sensitive to propylene glycol. Users report irritation with some versions of KX-826.

      community Im struggling with sebderm need help

      in Product  3 upvotes 1 month ago
      The user is struggling with seborrheic dermatitis and plans to try ciclopirox olamine after finding ketoconazole too drying. They are also using finasteride daily.

      community Minxodil collegen synthesis decrease?

      in Minoxidil  3 upvotes 1 year ago
      Minoxidil may age skin by slowing collagen synthesis, but using collagen peptides and a basic skincare routine might counteract this. Foam minoxidil could reduce systemic absorption and avoid alcohol-related side effects.

      community What’s the view on stemoxydine?

      in Product  4 upvotes 9 months ago
      Stemoxydine may work synergistically with minoxidil and finasteride for hair growth, but its effectiveness is debated, with some users experiencing minimal results and concerns about cost. Users suggest sticking to proven treatments like minoxidil and finasteride, while considering stemoxydine as an additional option.

      community Growth stimulants worth a damn besides minox?

      in Minoxidil  3 upvotes 2 years ago
      The user experiences side effects from minoxidil and is considering alternatives like stemoxydine and adenosine for hair regrowth and density, but finds options like caffeine and various oils unreliable. They are also using a 5AR inhibitor (finasteride).

      community Diy dutesteride please help MCT oil or PG?

      in Finasteride/Dutasteride  1 upvotes 4 months ago
      A user is making their own dutasteride solution using MCT oil but is concerned about its effectiveness and bioavailability. They are considering using propylene glycol or adding ethanol for better results, while others suggest the current dosage might be excessive.
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