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GlossaryPigmentation Disorders

conditions affecting skin, hair, or eye color due to melanin abnormalities

Pigmentation disorders are conditions that affect the color of your skin, hair, or eyes due to abnormal melanin production. These disorders can result in patches of skin that are lighter (hypopigmentation) or darker (hyperpigmentation) than the surrounding areas, and can be caused by genetic factors, sun exposure, or underlying health issues.

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community Gland treatment and Crude Oil Massage

in Treatment 7 years ago

Hair loss treatment involves gland treatment with iodine, liver extract, wild American ginseng, and black cohosh, along with crude oil scalp massage. The approach aims to stimulate hormones and improve blood circulation to promote hair growth.

community 1.5 years topical minox 0.5 ml twice (just temples) + 0.5 mg oral finasteride daily.

in Progress Pictures 664 upvotes 7 months ago

The user experienced hair regrowth and improved hair quality using topical minoxidil on temples and oral finasteride daily. They also noted thicker eyebrows and some side effects like minor erectile dysfunction.

community 2 % fucoidan significantly alleviated AGA symptoms, promoted hair growth, and increased hair density

in Research/Science 23 upvotes 8 months ago

2% fucoidan alleviated AGA symptoms, promoted hair growth, and increased hair density in mice. Fucoidan is considered safe for humans as a supplement and topical skincare product, with potential therapeutic effects against AGA.

community Making your own RT1640 in China

in Research/Science 4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

in Research/Science 66 upvotes 7 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 74 upvotes 1 year ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community Could microneedling for the next 5 years cause any permanent damage?

in Microneedling 22 upvotes 2 years ago

Microneedling for hair loss and its potential long-term effects. Some users believe it can cause fibrosis and scar tissue if done too frequently or deeply, while others claim it has improved their hair loss when done correctly. There is limited scientific research on the topic.

community Hair loss is holding me back from enjoying life and I'm wasting away my youth

in Chat 279 upvotes 2 months ago

A 31-year-old man feels depressed due to hair loss, using topical finasteride and previously tried minoxidil. Others suggest treatments like finasteride, minoxidil, hair transplants, or embracing baldness, highlighting the importance of mental health and self-acceptance.

community Justin Bieber got a hair transplant

in Transplants 1480 upvotes 1 year ago

Justin Bieber has had multiple hair transplants, with discussions on the cost and quality in places like Turkey. Despite using treatments like finasteride, his hairline appears unnatural to some.

community Why I Will be Accepting Baldness

in Chat 204 upvotes 3 years ago

User decides to accept baldness due to mental health issues with finasteride. Others suggest considering hair systems, topical finasteride, or RU58841 as alternatives.

community Topical Dutasteride is Here.

in Finasteride/Dutasteride 153 upvotes 5 years ago

The availability of Topical Dutasteride, a potential treatment for hair loss, which can be purchased without prescription from MinoxidilMax. Other treatments discussed include Topical Finasteride and PRP injections, with discussion around dosage, efficacy, side-effects and safety.

community Could Eating disorders induce secondary effects on finasteride?

in General 112 upvotes 8 months ago

A user experienced a loss of libido and anhedonia after severe dietary restriction while on Finasteride and Minoxidil for hair loss. They are considering reducing the Finasteride dose or taking a break to see if symptoms improve.

community CRISPR treatment for AGA on the horizon after approval for blood disorders

in Treatment 9 upvotes 2 years ago

CRISPR treatments for blood disorders have been approved, leading to discussions about its potential for treating hair loss (AGA). A study showed that editing a gene related to DHT sensitivity could lead to hair regrowth, suggesting CRISPR may eventually be used for AGA, but it's expected to be expensive and not soon available.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community DUPA, Non Responders and Connective Tissue Disorders

in Research/Science 9 upvotes 11 months ago

A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

community Hair Loss Causes Depression. Not Finasteride.

in Research/Science 188 upvotes 3 months ago

Finasteride and Dutasteride do not cause depression or mood disorders; hair loss itself may be a more significant factor. Some users experience side effects from Finasteride, but it is generally well-tolerated.

community Hair Loss Ruins Your Mind: 10x rate of BDD. PF S is not real

in Research/Science 39 upvotes 4 months ago

Hair loss is linked to a higher rate of body dysmorphic disorder (BDD), OCD, and depression. Finasteride and dutasteride are not linked to increased suicidal risk, though some users report mental health side effects.

community 20F: Should I Continue Minoxidil After ED Recovery for Hair Shedding?

in Minoxidil 199 upvotes 10 months ago

A 20-year-old female is considering whether to continue using minoxidil for hair loss after recovering from an eating disorder and iron deficiency. She is concerned about hair shedding and is advised to focus on nutrition and iron intake, with the option to taper off minoxidil gradually if she chooses to stop.

community Diffuse thinning is so fucked. Change in my from March til now

in Finasteride/Dutasteride 417 upvotes 9 months ago

The user experienced significant hair thinning despite using finasteride and minoxidil, leading to concerns about whether it's a temporary shed or a more serious issue. They plan to start using RU58841 and are advised to consult a doctor to rule out other causes like autoimmune disorders.

community Keratin microspheres - breakthrough

in Research/Science 14 upvotes 2 years ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community 17M biotin and minoxidil hair regrowth progress

in Progress Pictures 83 upvotes 2 years ago

A user's hair regrowth journey using biotin and minoxidil after initial treatments with Nizoral shampoo and Ketoconazole serum didn't work. The comments suggest the hair loss might not be male pattern baldness (MPB), but possibly Alopecia Areata, an autoimmune disorder, and recommend getting a second opinion and considering other treatments like corticosteroids.

community Possible causes for crown/top of head thinning even while on a “nuclear” stack? (MTF + fin + microneedling)

in What should I do? 2 upvotes 3 years ago

Trans woman experiences hair thinning despite low testosterone and treatments like finasteride and microneedling. Possible causes discussed include past eating disorder and current stack of medications and supplements.

community Hairloss is mentally exhausting

in Chat 24 upvotes 5 years ago

The conversation is about the mental toll of hair loss and seeking alternatives to finasteride. Suggestions include using minoxidil, considering pumpkin seed oil, and possibly seeking counseling for body dysmorphic disorder.

community Dont know what the hell is going on.

in Chat 6 upvotes 1 year ago

The user experienced rapid diffuse hair thinning for five years despite no signs of AGA or miniaturization. They tried finasteride and oral minoxidil without success and have checked thyroid, iron, and vitamin D levels.

community Hair loss returned suddenly and rapidly after a year on only oral minoxidil? Hair getting greasy fast.

in Chat 10 upvotes 2 years ago

User experienced sudden, rapid hair loss after a year on 2.5mg oral minoxidil. They are hesitant to use finasteride due to anxiety and depression concerns.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 4 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community The Real Reason For Hair Loss?

in Research/Science 5 months ago

Hair loss is linked to scalp fibrosis and tension, which result from chronic mechanical stress and androgenic signaling. Treatments include blocking androgens with finasteride, promoting hair growth with topical minoxidil, and improving scalp mobility through exercises.

community Mental Health and Finasteride Questions

in General 162 upvotes 1 year ago

A 20-year-old with anxiety and depression is considering finasteride for hair loss but is worried about potential side effects. They decide to consult a doctor and consider starting with a low dose, while also exploring topical finasteride as a potentially safer option.

community Autoimmune disease and balding

in Update 12 upvotes 1 year ago

A user diagnosed with Crohn's disease is concerned it might contribute to balding. They have been using keto shampoo, finasteride, and oral minoxidil, which improved their hair but not significantly.

community New study shows that microneedling is an ineffective hair loss treatment

in Research/Science 3 years ago

The effectiveness of microneedling as a hair loss treatment, with evidence from studies and anecdotal accounts from other users. It is suggested that combining microneedling with minoxidil or finasteride may be more effective than using microneedling alone, although some people have had success using only microneedling.