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    Did you mean Interferon-gamma?
    GlossaryInterferon-gamma

    protein that activates immune cells to fight infections and cancer

    Interferon-gamma (IFN-γ) is a type of protein called a cytokine that plays a crucial role in the immune system. It is produced primarily by T cells and natural killer (NK) cells and helps activate macrophages, enhance antigen presentation, and boost the body's defense against infections and cancer.

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      community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

      in Research/Science  132 upvotes 1 year ago
      Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  416 upvotes 1 year ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community Hair loss at age 23... Thyroid t4 value of 0.8

       4 upvotes 8 years ago
      A 23-year-old is experiencing hair loss, primarily at the top middle of the head, and is considering finasteride but is hesitant due to potential side effects. Other users share their positive experiences with finasteride, suggesting it is worth trying, while also discussing the importance of researching and monitoring for any side effects.

      community Fevipiprant 2019!

       15 upvotes 9 years ago
      The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

      community Why is it that low testosterone causes hair loss as well? How can I be balding?

      in Chat  158 upvotes 2 years ago
      The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

      community 35 MtF | 16 Months | Minoxidil + Dutasteride + Microneedling + Exosomes. Note that since I'm early in my transition (and I was coming from a bald state), I still have short hair. Very few MtF progress pictures here, I figure this might help some of you.

      in Transgender  125 upvotes 2 years ago
      A 35-year-old transitioning female (MtF) shared her hair regrowth journey using Minoxidil, Dutasteride, Microneedling, and Exosomes, starting from a bald state. Commenters discussed the impressive results, skin care routine, and the effects of estrogen on hair and skin.

      community Caffeine affects on oral minoxidil

      in Chat  3 upvotes 2 years ago
      Caffeine may interfere with oral minoxidil because caffeine increases blood pressure while minoxidil lowers it. Users discuss potential interactions and effects on hair loss treatment.

      community Can Pyrilutamide use stopp Minoxidil gains

      in Chat  3 upvotes 2 years ago
      The conversation discusses whether using pyrilutamide would interfere with minoxidil's ability to regrow hair, considering pyrilutamide is seen as a maintenance drug that stops shedding, while minoxidil promotes hair growth but causes initial shedding.

      community Shoutout to Zinc pyrithione and Piroctone olamine

      in Product  3 upvotes 1 year ago
      Zinc pyrithione and piroctone olamine are effective for reducing hair shedding, possibly more so than ketoconazole. There is a concern about zinc pyrithione shampoo interfering with minoxidil, but it's unclear if this is proven.

      community Did quitting caffeine turn me into a minoxidil responder?

      in Minoxidil  2 upvotes 2 years ago
      A user shared that after quitting caffeine and restarting oral minoxidil, they experienced significant hair regrowth, suggesting that caffeine might interfere with minoxidil's effectiveness by blocking adenosine receptors. They also mentioned side effects like water retention and dizziness, which subsided after a few weeks, and are not using any DHT blockers.

      community Thinking about adding PRP - any real downsides?

      in Treatment  7 upvotes 7 months ago
      The user has been using minoxidil, finasteride, dermastamping, and Nizoral for hair loss with initial success but is considering adding PRP due to slowed progress. Concerns about PRP include potential ineffectiveness and whether it could harm existing hair growth or interfere with current treatments.

      community 41M – On Finasteride 16 years with great results, now seeing temporal loss. Meds wearing off? Time to switch things up?

      in General  149 upvotes 9 months ago
      A 41-year-old has been using finasteride for 16 years with great results but is now experiencing temporal hair loss. Suggestions include switching to dutasteride, adding oral minoxidil, and considering a combination of treatments, while noting that supplements and weightlifting likely don't interfere with finasteride's effectiveness.

      community How to deal with mpb stress at an young age, Please help

      in Chat  6 upvotes 2 months ago
      A 17-year-old is stressed about mild male pattern baldness and is considering treatments like minoxidil and finasteride but is concerned about starting finasteride too young. Users suggest starting with minoxidil and considering finasteride at 18, while emphasizing the importance of consulting a doctor and not obsessing over hair loss.

      community Does Scalp tension = rise of DHT?

      in Research/Science  9 upvotes 1 year ago
      Scalp tension may contribute to hair loss by increasing DHT levels, with potential solutions like scalp massages and Botox. Concerns about finasteride's side effects were discussed, and some users shared personal experiences with alternative treatments like scalp massaging and Botox.

      community Stopping hairloss with pure willpower

      in Treatment  39 upvotes 5 months ago
      The conversation humorously discusses using "pure willpower" as a method to combat hair loss, alongside treatments like dutasteride, finasteride, and RU58841. The original poster claims that this unconventional approach, involving shouting affirmations and avoiding distractions, has led to noticeable hair regrowth.
      Treatment advice on balding with different hair colors

      community Treatment advice on balding with different hair colors

      in General  69 upvotes 6 months ago
      The user is seeking advice on hair loss treatments, considering options like finasteride, dutasteride, minoxidil, or a hair transplant. They are concerned about how their mixed hair color might affect a transplant.

      community Concerns About Black Hair Powder Affecting Hair Growth on Fin for 1 Week

      in General  57 upvotes 10 months ago
      The user started using finasteride three times a week and discovered black hair powder, which improved their appearance but raised concerns about potentially blocking hair pores. They are seeking advice on whether it's safe to use the powder without affecting new hair growth.

      community Which RU/Min combo would you go with?

      in Product  6 upvotes 11 months ago
      Choosing between two hair loss treatments, with a preference for a higher concentration of RU58841 and 5% minoxidil, avoiding oils like castor and argan that may hinder absorption.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  53 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.