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GlossaryCXCL10

signaling protein that attracts immune cells to inflammation sites

CXCL10, also known as Interferon gamma-induced protein 10 (IP-10), is a type of signaling protein called a chemokine. It plays a crucial role in the immune system by attracting white blood cells to sites of inflammation or infection. This protein is particularly important in conditions where the immune response needs to be regulated, such as autoimmune diseases and certain types of hair loss like alopecia areata.

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research Polymorphisms in the promoter regions of the CXCL1 and CXCL2 genes contribute to increased risk of alopecia areata in the Korean population

8 citations , January 2015 in “Genetics and Molecular Research”

Certain gene variations increase the risk of alopecia areata in Koreans.

Humanized CXCL12 Antibody Delays Onset and Modulates Immune Response in Alopecia Areata Mice: Insights from Single-Cell RNA Sequencing

research Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing

7 citations , October 2024 in “Frontiers in Immunology”

A humanized CXCL12 antibody may delay and treat alopecia areata by altering the immune response.

research Th1 Chemokine CXCL10 and Alopecia Areata: The Possible Target for the Treatment of Alopecia Areata

3 citations , January 2016 in “Journal of Clinical & Cellular Immunology”

Targeting CXCL10 may help treat alopecia areata.

CXCL12 Neutralizing Antibody Promotes Hair Growth in Androgenic Alopecia and Alopecia Areata

research CXCL12 Neutralizing Antibody Promotes Hair Growth in Androgenic Alopecia and Alopecia Areata

January 2024 in “International Journal of Molecular Sciences”

Blocking the protein CXCL12 with a specific antibody can increase hair growth in common hair loss conditions.

CXCL12 Inhibits Hair Growth Through CXCR4

research CXCL12 inhibits hair growth through CXCR4

April 2022 in “Biomedicine & Pharmacotherapy”

CXCL12 protein slows down hair growth through its receptor CXCR4. Blocking this can potentially increase hair growth.

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