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Did you mean Non-coding RNAs?

GlossaryNon-coding RNAs

molecules of RNA that regulate gene expression without making proteins

Non-coding RNAs (ncRNAs) are molecules of RNA that do not encode proteins but play crucial roles in regulating gene expression and maintaining cellular functions. They include various types such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), which can influence processes like cell growth, differentiation, and response to stress, making them important in both normal biology and disease states.

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community What new hair-loss treatments actually look exciting right now (Oct 2025)

in Research/Science 173 upvotes 7 months ago

New hair loss treatments include Breezula, PP405, ET-02, KX-826, GT20029, VDPHL01, and CosmeRNA, with some showing promise in reactivating stem cells and reversing greying. Breezula and VDPHL01 are highlighted as potential add-ons or alternatives to current treatments like finasteride and minoxidil.

community Journey against alopecia - Finasteride 3 month

in Progress Pictures 18 upvotes 4 years ago

A 26-year-old man from France started experiencing hair loss in September 2020 and began using finasteride in June 2021, reporting some improvement after three months without side effects. He plans to continue finasteride for a year before considering additional treatments like minoxidil or dermarolling.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community We need to keep these snake oil companies accountable.

in Treatment 120 upvotes 1 year ago

Biotin is being misleadingly marketed as a primary treatment for androgenic alopecia, overshadowing more effective treatments like finasteride and minoxidil. There is a call for increased awareness and accountability to prevent misinformation.

community Why is dht bad for scalp hair but good for hair on the rest of body?

in Satire 109 upvotes 2 years ago

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

community How do we only have two treatments to combat hair loss at this point in time?

in Chat 211 upvotes 2 years ago

The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 2 years ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

in Satire 353 upvotes 2 years ago

The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.

community End of Hair loss ( AGA ) ? Since they produce it in china probably we don’t need to wait other 10 yrs😁

in Treatment 268 upvotes 2 months ago

GT20029 is a new hair loss treatment in Phase 3 trials in China, using PROTAC technology to target androgen receptors, potentially with fewer side effects than finasteride and minoxidil. VDPHL01, a second-generation minoxidil, is also mentioned as potentially more effective.

community My Testosterone results before and after Finasteride

in Update 147 upvotes 4 years ago

Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 445 upvotes 5 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Hairloss has destroyed my Life completely

in Chat 339 upvotes 10 months ago

A young person is distressed about rapid hair loss despite using finasteride and recently starting oral minoxidil. Many suggest continuing treatment, considering dutasteride, and seeking therapy for mental health support.

community 15yo with severe anxiety from Norwood 2.5 and thinning

in Finasteride/Dutasteride 15 upvotes 1 year ago

A 15-year-old experiencing hair loss and anxiety is using minoxidil and microneedling but is advised against starting finasteride or dutasteride due to age. The discussion emphasizes consulting a doctor, considering hormonal evaluations, and exploring non-medication coping strategies.

community Help non-recipient cown after hair transplant - besides Fin and Min?

in General 62 upvotes 11 months ago

The user had a hair transplant and is using oral minoxidil and finasteride but seeks advice for treating the crown area. They are looking for additional recommendations for non-transplanted areas.

community Creatine - coming off and back on. Findings.

in Progress Pictures 62 upvotes 2 years ago

Stopping creatine led to reduced hair loss for some, despite no proven link between creatine and hair loss. Users shared experiences, with some using minoxidil and finasteride to manage hair loss.

community Hold up... CosmeRNA/SAMiRNA is actually coming real soon?

in Technology 31 upvotes 3 years ago

A user discovered CosmeRNA, a new hair loss treatment with clinical research backing, set to release soon. The conversation revolves around its potential effectiveness, cost, and how it compares to existing treatments like Minoxidil and Finasteride, with some users expressing hope for a side-effect-free option.

community hmi115 is coming. Prepare yourselves for what's coming

in Technology 106 upvotes 2 years ago

The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

community Update on dut and min (thought I was a non responder)

in Update 11 upvotes 1 week ago

The user is using dutasteride and minoxidil for hair loss and noticed new hair growth after initially thinking there was no progress. Encouragement was given to continue the treatment as it takes time to see full results.

community Coming up on 3 months of treatment

in Progress Pictures 182 upvotes 2 months ago

The user is happy with their hair regrowth after three months of using a 4-in-1 pill containing minoxidil, dutasteride, finasteride, and biotin, along with microneedling and saw palmetto shampoo. They experienced initial shedding but are pleased with the progress and have not had any side effects.

community Seeking advice from dut non-responders who used RU

in Update 1 upvotes 9 months ago

The conversation discusses hair loss treatments, specifically the use of RU58841 by individuals who did not respond to dutasteride. Users share experiences with maintaining hair using RU58841 and mention trying pyrilutamide and the upcoming availability of pp405.

community I'm becoming non-responder to minoxidil. What's going on?

in Minoxidil 7 upvotes 9 months ago

The user experienced reduced effectiveness of minoxidil after consistent use, despite using dutasteride to maintain hair. They are considering alternatives like microneedling and exploring options like hair transplants due to dissatisfaction with current hair density.

community Found a winning combo for a non/weak-responder

in Research/Science 4 upvotes 1 year ago

A user found a successful hair loss treatment using a combination of finasteride, dutasteride, minoxidil, and RU58841. They plan to switch to a purely topical regimen with finasteride, RU58841, and minoxidil.

community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

in Minoxidil 78 upvotes 2 years ago

A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

community oral minoxidil is coming in clutch fr

in Satire 641 upvotes 3 years ago

. This conversation is a satire post about a user who appears to have an abundance of hair, with other users commenting and asking questions about the treatments they use for their hair loss. Treatments discussed include minoxidil and finasteride.

community Baby hair growth from non existent to existing.

in Progress Pictures 173 upvotes 7 months ago

A user shared progress pictures showing hair regrowth after using minoxidil and finasteride for several months. Despite skepticism, the user reports noticeable improvement and aims to motivate others with hair loss.

community PSA: Fin/Dut are NON-NEGOTIABLE

in Finasteride/Dutasteride 688 upvotes 1 year ago

Finasteride and dutasteride are essential for stopping hair loss, while natural remedies are ineffective. Minoxidil can be added if needed, but blocking DHT is crucial.

community Anyone excited for CosmeRNA coming this month?

in Product 171 upvotes 3 years ago

CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

community My hair is coming back, in as little as 11 days, is that normal?

in Chat 7 upvotes 6 years ago

A user reports significant hair regrowth in 11 days using 1mg finasteride daily and 2ml minoxidil daily, and questions if they can maintain their hair with just minoxidil and a good shampoo. They express concern about potential side effects of finasteride.

community 9 months fin 0.33mg daily - everything’s coming up millhouse

in Progress Pictures 81 upvotes 2 years ago

User started oral finasteride 0.33mg daily and later made a topical solution with cetirizine and stemoxydine. They experienced hair growth progress after 8-9 months and discussed factors affecting their results.

community 1 month Pyrilutamide. A non responders story to everything.

in Research/Science 218 upvotes 3 years ago

My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.