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Did you mean Olfactory Receptor?

GlossaryOlfactory Receptor

specialized protein in the nose that detects odors

An olfactory receptor (OR) is a specialized protein found in the sensory neurons of the nose that detects odor molecules. When an odor molecule binds to an olfactory receptor, it triggers a signal that is sent to the brain, allowing us to perceive and identify different smells. These receptors are part of a large family of G-protein-coupled receptors and are crucial for the sense of smell.

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community Sandalore: a scientific homemade approch

19 upvotes 7 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community Sandalore experiment

17 upvotes 7 years ago

A user added sandalore to minoxidil for hair loss, observing some vellus hair growth and less scalp inflammation. Others tried sandalore with mixed results, discussing dosage and effectiveness compared to minoxidil and finasteride.

community AH-001 another topical AR degrader beside GT20029, completed Phase I

in Research/Science 10 upvotes 7 months ago

AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.

community Since there is so much hype for cosmeRNA and HMI-115...

in Chat 44 upvotes 3 years ago

Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

community Actifolic RU58841 with octopirox?

in Treatment 1 upvotes 4 years ago

The conversation discusses using RU58841 with octopirox or essential oils for hair loss treatment. The user is seeking advice on which variation to try.

community PP405 is NOT gray market jxl069

in Technology 26 upvotes 5 months ago

PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

community rudirect ru58841 seems bunk to me

in Treatment 6 upvotes 1 month ago

RU58841 from rudirect caused more hair shedding and itch, while anageninc's RU58841 improved the situation. Users are concerned about the quality and authenticity of RU58841 from different suppliers, including those from China.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 3 years ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community 5ar alpha reductase stimulation is different depending on whether it’s type 1 or 2

in Hair Systems 17 upvotes 2 years ago

The conversation discusses how different factors can stimulate type 1 and type 2 isoforms of 5-alpha reductase, which are enzymes linked to hair loss. Specific treatments mentioned include oral Dutasteride and topical Finasteride.

community Good lord! Serioxyl stemoxydine smells TERRIBLE

in Product 14 upvotes 2 years ago

The conversation is about a user complaining about the strong smell of a stemoxydine serum used for hair loss. Other users suggest that the product might be counterfeit due to its unpleasant odor.

community JXL082 is not PP405 and Everychem followed the wrong lead

in Research/Science 43 upvotes 10 months ago

JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

community OND-1 "Cyclosporine A” New hair loss treatment

in Research/Science 28 upvotes 2 months ago

Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 year ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community RU58841 for 10 months- no results. Anyone else?

in Chat 1 upvotes 5 months ago

RU58841 not working for hair loss after 10 months. Concerns about purity of experimental drugs.

community What is the best legit source of RU58841 in the UK?

in Product 6 upvotes 1 year ago

A user is seeking a trusted supplier for RU58841 in the UK, expressing doubts about their current source, rudirect, and considering Anagenic and receptorchem. They are asking for recommendations for other suppliers.

community Anyone try RU58841 from this brand? truth진실

in Product 4 upvotes 9 months ago

The conversation discusses skepticism about the effectiveness and formulation of a $10 RU58841 gel from a Korean brand, questioning if ethanol is used to hold the active compounds. Concerns are raised about the feasibility of selling it at such a low price.

community ASC-J9: Poor man’s GT-20029 that might work for regrowth. Anyone try this stuff?

in Research/Science 3 years ago

The potential hair regrowth benefits of ASC-J9, a synthetic modified version of curcumin that is said to be more effective than Minoxidil and Finasteride. Reports from users suggest good thickening and temple regrowth with topical use at 0.025% concentration.

community Ru 58841 and essential oils question

in Treatment 3 upvotes 4 years ago

The user discusses using essential oils like peppermint, rosemary, tea tree, and lavender to improve hair thickness and seborrheic dermatitis. They plan to add RU58841 to their routine and seek advice on using it alongside the essential oils without interference.

community Fluridil downregulates androgen receptor expression?

in Research/Science 1 upvotes 2 years ago

Fluridil may decrease the number of androgen receptors in hair follicles by up to 95%. This suggests a different action mechanism from other non-steroidal antiandrogens like RU58841, indicating they might be used together.

community Published in Nature: Osteopontin, a protein involved in the growth of hair on moles could be the key to our troubles.

in Research/Science 12 upvotes 2 years ago

Osteopontin, a protein involved in hair growth on moles, may help with hair loss. However, it is also linked to Alzheimer's, cancer, and bone development, so caution is advised.

community legit source for RU58841 in Germany?

in Treatment 3 upvotes 5 months ago

The conversation is about finding a legitimate source for RU58841 in Germany, with suggestions including Receptorchem and GeneTherica. Anageninc and Chemyo do not deliver to Germany.

community Any ru58841 users here, where do you get it from?

in General 37 upvotes 6 months ago

The conversation is about sourcing RU58841 for hair loss treatment, with a focus on finding reputable sellers. The user plans to use 10mg/ml daily, split into two doses, prioritizing quality over price.

community norwood 7 from both sides of family, destined to go bald 17M

in Chat 9 upvotes 3 years ago

17M approaching Norwood 2, using topical minoxidil and considering finasteride, oral minoxidil, and pyrilutamide. Plans to study dermatology and possibly get a hair transplant at 25 if treatments don't work.

community Any updates on RCH-01?

in Question 11 upvotes 6 years ago

The conversation is about seeking updates on the hair loss treatment RCH-01, specifically its next phase and any news from Shiseido. The user recalls someone being in contact with a researcher or company representative.

community any Ru58841 user ? + What do I need to expect?

in Product 10 upvotes 1 year ago

The user is considering adding RU58841 to their current hair loss treatment of finasteride and minoxidil, but is concerned about potential side effects like hairline recession and shedding. Some users report positive results with RU58841, while others experience side effects such as chest pain and dizziness.

community Anyone here who’s using Alfatradiol (17a-Estradiol) in consistency with some results?

in Treatment 8 upvotes 5 years ago

User discusses Alfatradiol (17a-Estradiol) as a potential hair loss treatment with mixed results. Concerns include low dosage, receptor theory, and possible increased aromatase activity on scalp.

community Oxytocin Pathway and Cinnamic Acid Research

in Research/Science 15 upvotes 2 years ago

The conversation discusses the potential of cinnamic acid for hair growth. It also mentions treatments like Minoxidil, finasteride, and RU58841.

community JW Pharmaceutical shows superiority of 'JW0061' in hair growth over existing treatments in US

in Research/Science 99 upvotes 2 years ago

JW0061 shows superior hair growth results compared to existing treatments, with significant increases in hair follicles. The Wnt/β-catenin pathway is crucial for hair growth, and JW0061 activates this pathway effectively.

community Anageninc RU58841 is legit & my experience

in Research/Science 6 upvotes 2 years ago

The user experienced side effects from RU58841, including dry eyes and potential eyesight issues, and decided to stop using it. They confirmed the product's legitimacy but advised caution due to its experimental status and lack of safety data.

community Discount on RU58841 at Anagen Inc with coupon code - FYI

in Product 6 upvotes 1 year ago

A user shared a discount code for RU58841 from Anagen Inc, which some users find effective for hair loss without side effects. Another user expressed skepticism about the safety of RU58841 due to limited research.