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GlossaryRUNX1

regulates gene expression crucial for blood cell development

RUNX1, also known as Runt-related transcription factor 1, is a gene that plays a crucial role in the regulation of gene expression during the development of blood cells. Mutations in RUNX1 are associated with various blood disorders, including acute myeloid leukemia (AML), making it a significant focus in both clinical and research settings.

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community Minoxidil&Finasteride 7 months progress

in Progress Pictures 936 upvotes 2 years ago

A user shared their 7-month progress using Minoxidil and Finasteride for hair loss, which significantly reversed their aging appearance. They applied Minoxidil twice daily, took 1mg Finasteride once daily, micro-needled weekly, maintained a high protein diet with vitamins and biotin, and recommended a balanced lifestyle for best results.

community Feeling myself again after 5 months

in Progress Pictures 470 upvotes 3 years ago

A user's progress pictures which show the effects of using finasteride and minoxidil for hair growth, along with keto shampoo; other users shared their experiences with similar conditions, offering advice on treatments and encouraging the original poster to keep going.

community Ruxolitinib - Start of a case study

in Research/Science 10 upvotes 2 years ago

The conversation is about a user trying a new hair loss treatment, Ruxolitinib, alongside their existing regimen of finasteride, minoxidil, ketoconazole shampoo, and microneedling. They plan to apply Ruxolitinib to their temples daily for 1-2 months.

community Hives/Rash from Kx 826 Pyrilutamide???

in Chat 1 upvotes 1 year ago

OP developed hives after using Kx 826 (Pyrilutamide) 1% twice daily for 3 weeks. The hives appeared on the arms, chest, and groin area.

community Kintor KX -826 Pyrilutamide Adds 1 Year Phase 3 Trial For Safety

in Technology 54 upvotes 2 years ago

KX-826/pyrilutamide is undergoing an additional one-year safety and efficacy trial in China after a six-month study. Some participants speculate on the reasons for the extended trial and discuss the potential of other treatments.

community To everyone who cant use FIN and doesnt want to use RU

in Treatment 33 upvotes 1 year ago

A new hair loss treatment, KX-826, is being discussed as a stronger and safer alternative to RU58841 and finasteride. Opinions are mixed, with some users skeptical about its effectiveness and others considering it as part of their regimen.

community KX826 is better than RU58841. A legitimate option for those who cant use fin or dut.

in Research/Science 6 upvotes 2 months ago

KX826 is considered a legitimate option for those who cannot use finasteride or dutasteride, but many users report it as ineffective compared to RU58841. RU58841 is favored by some due to anecdotal evidence of effectiveness, despite the lack of published clinical data.

community KX-826 Pyrilutamide1% coming soon

in Update 152 upvotes 1 year ago

KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

community KX-826 1% Phase II Results from China Just Dropped

in Research/Science 37 upvotes 10 months ago

KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

community Any point in microneedling with RU?

in Microneedling 1 upvotes 9 months ago

Microneedling with RU58841 may not be necessary since RU works topically by occupying receptors before DHT binds. RU58841 is a topical anti-androgen.

community Kintor has released an investor relations memo regarding Chinese Phase III trials for Pyrilutamide

in Update 51 upvotes 2 years ago

Kintor's Pyrilutamide (KX-826) showed hair growth in Chinese Phase III trials but did not significantly outperform placebo. The treatment was safe with no major adverse reactions reported.

community KX-826 , a small change in the pipeline

in Research/Science 6 upvotes 4 months ago

KX-826 is undergoing trials for hair loss treatment, showing similar effectiveness between 0.5% and 1.0% dosages, with mild side effects compared to finasteride. Users discuss combining KX-826 with other treatments like minoxidil and clascoterone for better results.

community Does RU58841 potentially cause cancer?

in Research/Science 1 year ago

RU58841 may pose cancer risks due to its antiandrogen properties and lack of long-term safety data. Using it is considered a high-risk experiment with unknown potential for harm.

community 3 month Ru58841,minox,microneedling transformation while blasting 2g of gear

in Is this regrowth? 188 upvotes 1 month ago

Significant hair regrowth was achieved using RU58841, minoxidil, and microneedling during a high-dose steroid cycle. The user reported no side effects from RU58841 and plans to continue the regimen.

community Has anyone figured out what causes the cardiovascular issues with RU?

in Chat 4 upvotes 1 year ago

RU58841 and Minoxidil can cause heart-related side effects like chest pain and heart racing. Pyrilutamide is suggested as a safer alternative, though it's new and costly.

community pyrilutamide log from someone who couldnt take fin/min/ru due to sideeffects

in Progress Pictures 105 upvotes 3 years ago

A user (seblt) who has had side effects from finasteride, minoxidil and RU58841 but is now trying pyrilutamide as a last resort, with other users providing advice and support. They have already seen some baby hairs growing after 10-14 days of treatment and will provide updates in 1-2 weeks.

community day 107 of kx826 .5% . 1+ years on topical minoxidil.

in Progress Pictures 18 upvotes 1 year ago

The user has been using topical minoxidil for over a year and added kx826/pyrilutamide to improve hair growth, avoiding finasteride due to side effects like lowered libido and panic attacks. They report positive results with reduced shedding and healthier hair, particularly in areas previously unresponsive to minoxidil.

community Making your own RT1640 in China

in Research/Science 4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community Ru-58841 vs KX-826/pyrilutamide while on steroids

in Finasteride/Dutasteride 5 upvotes 1 year ago

The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

community Has anyone used KX-826 as a MONOTHERAPY?

in Research/Science 15 upvotes 3 years ago

Exploring potential treatments for hair loss, such as Minoxidil, Finasteride, RU58841 and Pyrilutamide. The user is looking for feedback on whether KX-826 can be used successfully as a single therapy to stop the miniaturization process.

community cosmeRNA finally now it's pyrilutamide turn

in Chat 48 upvotes 3 years ago

Hair loss treatments discussed include cosmeRNA, minoxidil, finasteride, RU58841, and pyrilutamide. Users debate effectiveness, side effects, and upcoming treatments, with some expressing skepticism and others optimism.

community Waiting to start treatment until Kintor KX-826 Phase 2 data is published?

in Chat 17 upvotes 4 years ago

People are waiting for KX-826 (Pyrilutamide) Phase 2 data to decide on hair loss treatments, with some considering finasteride or minoxidil in the meantime. Pyrilutamide is seen as a potentially stronger and safer alternative to finasteride, but concerns about side effects and availability remain.

community Signs of life. Ru, topical fin/min, mk677, micro needling

in Progress Pictures 192 upvotes 4 years ago

The conversation discusses using RU58841, topical finasteride/minoxidil, MK677, and microneedling as treatments for hair loss. MK677 is mentioned as a growth hormone that improves hair health and recovery from microneedling.

community 11 month Progress 17-18yo with RU58841*

in Progress Pictures 49 upvotes 1 year ago

The user experienced hair regrowth using a combination of Minoxidil, Finasteride, and RU58841, with Minoxidil used initially and the other treatments added later. The user believes the combination of Finasteride and RU58841 contributed to the regrowth, with RU sourced from MVsupplement.

community RU58841 users — how do you find a reliable source?

in Research/Science 2 upvotes 9 months ago

Users discuss finding reliable sources for RU58841, focusing on lab tests, batch consistency, and community reputation. Some mention using alternatives like pyrilutamide.

community Anageninc no longer sell KX-826 (Pyrilutamide) due to receiving a cease and desist letter from Kintor :(

in Update 19 upvotes 3 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. Anageninc stopped selling KX-826 (Pyrilutamide) due to a cease and desist letter from Kintor, but this may indicate promising study results and a potential 2024 release.

community Ru-58841 or KX-826 (Pyrilutamide)?

in Treatment 11 upvotes 3 years ago

Exploring potential treatments for hair loss, with the focus being on comparing RU58841 and Pyrilutamide. Finasteride, Dutasteride, oral Minoxidil, microneedling, topical Minoxidil, Biotin, Zinc, Vitamin D and Nizoral are also discussed as part of a treatment stack.

community Can mixing RU with min compounded with tretinoin cause the RU to go sytemic

in Chat 3 upvotes 5 months ago

Mixing RU58841 with minoxidil compounded with tretinoin is discussed, with concerns about systemic absorption. Topical dutasteride and finasteride are also mentioned as treatments, with varying personal experiences and concerns about side effects.

community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc

in Treatment 22 upvotes 2 years ago

Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.

community RU58841 powder from lab supplier tested at free drug testing service.

in Research/Science 8 upvotes 1 year ago

Two Chinese suppliers provided legitimate RU58841, confirmed through a free drug testing service. The vendors were Shaanxi Greenyo Biotech and Lyphar, found on Made-in-China.