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GlossaryTeriflunomide

medication used to treat multiple sclerosis by reducing immune activity

Teriflunomide is a medication primarily used to treat multiple sclerosis (MS), a condition where the immune system attacks the protective covering of nerves. It works by inhibiting the function of certain immune cells, thereby reducing inflammation and the frequency of MS flare-ups.

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community Topilutamide (fluridil) raw active?

in Research/Science 7 upvotes 5 years ago

Topilutamide is a potential hair loss treatment between Clascoterone and RU58841. Users discuss finding Topilutamide powder and its possible benefits for those who can't afford or tolerate other treatments.

community Pyrilutamide available at Actifolic now

in Research/Science 15 upvotes 3 years ago

Pyrilutamide, a new hair loss product with the potential to be more effective than RU58841 and safer than CB, but expensive.

community fluridil (topilutamide) vs. cb-03-01 (clascoterone)

in Research/Science 5 upvotes 2 years ago

The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.

community Should I consider switching from Fluridil to Pyrilutmide?

in Treatment 12 upvotes 1 year ago

The conversation is about considering switching from Fluridil to Pyrilutamide for hair loss treatment. Pyrilutamide is suggested to be more effective, with a recommendation to use the 1% variant twice daily.

community MY ANECDOTAL REPORT ON SAFETY OF ALFATRADIOL AND FLURIDIL COMBINED WITH FINASTERIDE! COMPOUNDS APPROVED FOR MPB IN THE EUROPEAN UNION (i cant comment on the efficacy, cause i am on other treatments)

in Treatment 9 upvotes 4 years ago

The safety of combining alfatradiol and fluridil with finasteride as a potential treatment for male pattern baldness, which is approved in the European Union. Other treatments such as minoxidil and RU58841 were also discussed.

community Pyrilutamide for non-5AR users?

in Treatment 10 upvotes 1 year ago

Pyrilutamide is considered by some as an alternative for those avoiding 5AR inhibitors like finasteride and dutasteride, but opinions on its effectiveness vary. Some users report similar results with fluridil and pyrilutamide, while others find pyrilutamide less effective compared to prescription treatments.

community Quitting Alfatradiol after 4 months

in Product 5 upvotes 1 year ago

The user stopped using Alfatradiol after 4 months due to no hair improvement and side effects like dry scalp and gallbladder pain. They are considering trying topilutamide, which is suggested as an alternative.

community Alfatradiol and Fluridil enough? Thoughs on topical fin?

in Treatment 4 upvotes 2 years ago

The user is currently using alfatradiol and fluridil for hair loss and is considering adding low-dose topical finasteride but is concerned about potential side effects due to past mental health issues. They are seeking others' experiences with these treatments and their effectiveness.

community Fluridil/topilutamide experince

in Treatment 5 upvotes 2 years ago

A user is trying fluridil/topilutamide for hair loss and experiencing side effects like pain in the testicles and genital discomfort. They previously had adverse effects with finasteride, dutasteride, and RU58841, and are considering other treatments like topical dutasteride and spironolactone for maintenance before a hair transplant.

community Pyrilutamide or RU Monotherapy?

in Treatment 6 upvotes 3 years ago

Using Pyrilutamide or RU as monotherapy for hair loss? Share experiences.

community Kintor pyrilutamide presentation?

in Research/Science 12 upvotes 3 years ago

The conversation is about whether the phase 2 results for pyrilutamide, a potential hair loss treatment, were presented at a dermatology convention and inquiries about the completion of phase 3 trials. Specific treatments mentioned include pyrilutamide.

community Pyrilutamide and RU alternatives?

in Treatment 1 upvotes 1 year ago

Pyrilutamide is officially available for purchase, and users suggest Fluridil as an alternative topical anti-androgen. Some users report positive results with pyrilutamide from Koshine.

community 2nd day on pyrilutamide - what I noticed so far

in Treatment 7 upvotes 3 years ago

The user started using a hair loss treatment called pyrilutamide and experienced mild chest discomfort and tightness, similar to previous side effects from RU58841. They plan to reduce the dosage due to these side effects and will provide an update on the results in 1-2 months.

community I'm very skeptical about pyrilutamide

in Product 2 upvotes 4 months ago

Pyrilutamide's effectiveness is questioned due to overstated claims and previous trial ineffectiveness, with some users opting for finasteride instead. Despite skepticism, some consider adding pyrilutamide to their regimen alongside treatments like bicalutamide.

community Fluridil solution at Actifolic

in Treatment 4 upvotes 3 years ago

Fluridil, also known as Topilutamide or Eucapil, is discussed as a treatment for hair loss. It is noted as an androgen receptor antagonist, not a vasodilator.

community Pyrilutamide Phase 3 on its way

in Treatment 128 upvotes 4 years ago

Pyrilutamide Phase 3 approved, starting early 2022 with 416 subjects for 24 weeks. Drug potentially better than RU and Breezula, with some users reporting no side effects.

community Pyrilutamide - your experience?

in Product 12 upvotes 3 years ago

The conversation is about the lack of improvement in hair loss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.

community Pyrilutamide +Alfatradiol 0.1% , no Hairloss anymore

in Treatment 43 upvotes 1 year ago

OP experienced diffuse thinning for 11 years and used Minoxidil and Finasteride previously. They now use Pyrilutamide 0.5% and Alfatradiol 0.1%, resulting in significantly reduced hair loss.

community Why was fluridil abandoned and never made past phase 2?

in Chat 4 upvotes 4 years ago

Fluridil was abandoned due to its weak effectiveness and low binding affinity to the androgen receptor, making it less competitive against DHT and testosterone. Users discuss its limited results compared to other treatments like pyrilutamide and RU58841.

community Swapping from Fluridil to Pyrilutimide?

in Treatment 1 upvotes 5 months ago

The conversation discusses hair loss treatments, with the main focus on using Fluridil and considering switching to Pyrilutamide. Other treatments mentioned include minoxidil, topical finasteride, nizoral shampoo, and saw palmetto supplements, with advice to stick with Fluridil for at least six months before considering alternatives.

community pyrilutamide GB update please? Anything no matter how big or small

in Update 34 upvotes 4 years ago

The effects of Finasteride on hair loss and its side-effects, such as aching balls. The user has been taking it for two years with no changes to the symptom.

community Pyrilutamide with Alfatradiol and minoxidil (23M)

in Treatment 2 upvotes 6 months ago

The user experienced side effects from a hair loss treatment and is considering using pyrilutamide, alfatradiol, and possibly minoxidil. They are unsure about starting minoxidil immediately or waiting to see the effects of the other treatments.

community 0.25 alfatradiol or 0.5 Pyrulitamide ?

in Product 4 upvotes 8 months ago

The conversation is about choosing an anti-androgen for hair loss treatment, with options being alfatradiol and pyrilutamide. Alfatradiol is considered a better choice due to its established use, while pyrilutamide is more experimental.

community Pirfenidone - The answer to fibrosis and baldness

in Treatment 19 upvotes 4 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

community If I can’t tolerate 5ari, should I try Pyrilutamide 1%?

in Treatment 4 upvotes 1 year ago

The conversation is about considering pyrilutamide 1% as an alternative treatment for hair loss due to intolerance to 5-alpha reductase inhibitors. Some users suggest it might be effective, while others view it as a temporary solution.

community Using Pyrilutamide next to RU58841 good? Pyri stronger than Fluridil?

in Treatment 3 upvotes 2 years ago

The user plans to use RU58841 in the morning and Pyrilutamide in the evening for hair loss treatment, considering replacing Fluridil with Pyrilutamide. They believe Pyrilutamide is effective.

community pyrilutamide phase 2 results right here, thanks to user Glaringbooch

in Chat 43 upvotes 4 years ago

Pyrilutamide, a new drug being tested to combat hair loss that has been found to perform comparably or better than finasteride and dutasteride in the initial 6 months of treatment with minimal reported side effects.

community I think it’s time to drop Pyrilutamide at this point?….

in Update 29 upvotes 3 years ago

A user who has been using Pyrilutamide for 5 months with no results, and other users suggesting they switch to RU58841 or stick to their treatment plan for at least one year.

community Pyrilutamide - Worth it if can’t use Fin?

in Research/Science 4 upvotes 1 year ago

Pyrilutamide is being discussed as an alternative for those who can't use finasteride, but users report it may be ineffective at low concentrations. Some users are combining it with minoxidil, microneedling, and other treatments, but results vary.

community Best carrier for pyrilutamide?

in Update 9 upvotes 3 years ago

The conversation is about adding a low dose of pyrilutamide to a hair loss treatment regimen. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.