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Did you mean Dihydrotestosterone?

GlossaryDihydrotestosterone

potent androgen hormone derived from testosterone

Dihydrotestosterone (DHT) is a potent androgen hormone derived from testosterone through the action of the enzyme 5-alpha-reductase. It plays a crucial role in the development of male characteristics and is also implicated in conditions like androgenic alopecia (male pattern baldness) and benign prostatic hyperplasia.

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Research

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The Efficacy of Dihydrotestosterone Transdermal Gel Before Primary Hypospadias Surgery: A Prospective, Controlled, Randomized Study

research Re: The Efficacy of Dihydrotestosterone Transdermal Gel Before Primary Hypospadias Surgery: A Prospective, Controlled, Randomized Study

1 citations , June 2008 in “The Journal of Urology”

Dihydrotestosterone gel before hypospadias surgery led to less scarring but raised concerns about potential psychological effects and skin changes.

research The Effects of Transdermal Dihydrotestosterone in the Aging Male: A Prospective, Randomized, Double Blind Study

110 citations , April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Original Research—Endocrinology: Comparison of the Steady-State Pharmacokinetics, Metabolism, and Variability of a Transdermal Testosterone Patch Versus a Transdermal Testosterone Gel in Hypogonadal Men

research ORIGINAL RESEARCH—ENDOCRINOLOGY: Comparison of the Steady‐State Pharmacokinetics, Metabolism, and Variability of a Transdermal Testosterone Patch Versus a Transdermal Testosterone Gel in Hypogonadal Men

38 citations , February 2005 in “The journal of sexual medicine”

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

research Assessment of efficacy and safety of dapsone gel 5% in the treatment of acne vulgaris

1 citations , October 2019 in “مجله كليه طب الكندي”

Dapsone gel 5% is effective and safe for treating acne.

Design and Development of Epigallocatechin Gallate and Fenugreek Seed Extract Loaded Nanosponge-Based Aloe Vera Gel for Treating Alopecia Areata

research Design and development of Epigallocatechin gallate and Fenugreek seed extract loaded Nanosponge based Aloevera gel for treating Alopecia Areata

June 2026 in “International Journal of Drug Delivery Technology”

The developed aloe vera gel with green tea and fenugreek extracts may effectively treat hair loss.

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Community Join

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community 18 months. Dutasteride, RU58841, Minoxidil, Microneedling, Nizoral, T/GEL

in Progress Pictures 165 upvotes 5 years ago

A 28 year old man's 18-month journey to treat his hair loss with Dutasteride, RU58841, Minoxidil, Microneedling, Nizoral and T/GEL. He experienced some side effects along the way, including translucent semen and scalp less oily.

community Pirfenidone - The answer to fibrosis and baldness

in Treatment 20 upvotes 4 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

community Finally live! alcohol-free, propylene glycol–free topical finasteride foam

in Update 15 upvotes 9 months ago

A new alcohol-free, propylene glycol-free topical finasteride foam is available for prescription in Canada and the USA, offering a cleaner alternative for hair loss treatment. The product also offers a combination of 0.1% finasteride with 5% minoxidil and aims to be affordable and less irritating for sensitive scalps.

community Article of all potential future cures

in Treatment 25 upvotes 1 year ago

Ritlecitinib and PP405 show promise for hair regrowth. Diagnosing the cause of hair loss is crucial before treatment.

community 9 month update 1st slide 2020 at my worst vs today. 2nd slide 9 months ago vs today. 3rd, wet hair. 4th, hairline. 5th, damp hair. 6th crown view. 7th, brushed back. 8 & 9, hair in high Summer humidity. 10th, no lighting.

in Progress Pictures 342 upvotes 2 years ago

User shared 9-month hair regrowth progress using a Fin/Min spray from HIMS, with additional microneedling. Other users praised the results and discussed the effectiveness of topical treatments.

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Clinics

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Learn

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learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn GT20029

research compound made to degrade androgen receptors in scalp

learn Fluridil

a topical anti-androgen with less systemic involvement

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Experts

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