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A Novel Approach Against Male Pattern Hair Loss With Topical Dimethylglycine Sodium Salt (DMG-Na) and Caffeine: Efficacy of a 24-Week, Double-Blind, Randomized, Placebo-Controlled Trial

research A Novel Approach Against Male Pattern Hair Loss With Topical Dimethylglycine Sodium Salt (DMG-Na) and Caffeine: Efficacy of a 24-Week, Double-Blind, Randomized, Placebo-Controlled Trial

August 2025 in “Journal of Cosmetic Dermatology”

The shampoo with DMG-Na and caffeine effectively reduces hair loss and improves hair density in men.

research P33 Quantification of Metabolic Pathways in Human Hair Follicles and Their Response to Caffeine and N,N-Dimethylglycine

January 2026 in “British Journal of Dermatology”

Caffeine and DMG increase calcium influx in hair follicle cells without being toxic.

research Topically Applied N,N-Dimethylglycine Sodium Salt Enhances Human Skin Blood Flow by Inducing Endothelial Nitric Oxide Release

May 2024 in “The journal of investigative dermatology/Journal of investigative dermatology”

Applying DMG-Na to the skin increases blood flow and may help with skin conditions.

N,N-Dimethylglycine Sodium Salt Exerts Anti-Inflammatory Effects in Dermatitis Models and Activates Human Epidermal Keratinocytes

research N,N-Dimethylglycine Sodium Salt Exerts Anti-Inflammatory Effects in Dermatitis Models and Activates Human Epidermal Keratinocytes

July 2023 in “International Journal of Molecular Sciences”

N,N-Dimethylglycine Sodium Salt helps reduce skin inflammation and improves skin cell growth and healing.

research Boosting Skin Microcirculation for Androgenetic Alopecia: Does It Work?

February 2025 in “Journal of Investigative Dermatology”

DMG-Na may help reduce hair loss and improve hair growth, but more research is needed.

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community Caffeine + Dimethylglycine (DMG) Shampoo research

in Research/Science 6 upvotes 1 year ago

A user discusses the potential of caffeine and DMG in shampoo for treating hair loss, citing a pending patent and personal plans to test it. They find it more convenient than using minoxidil, tretinoin, and microneedling.