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Did you mean Double-stranded RNA?

GlossaryDouble-stranded RNA

molecule with two complementary RNA strands bound together

Double-stranded RNA (dsRNA) is a molecule consisting of two complementary strands of RNA that are bound together, similar to the structure of DNA. In biological systems, dsRNA is often a signal of viral infection, triggering immune responses in cells. It is also used in research and therapeutic applications, such as RNA interference (RNAi), to silence specific genes.

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Double-Stranded RNA Induces Inflammation via the NF-κB Pathway and Inflammasome Activation in the Outer Root Sheath Cells of Hair Follicles

research Double-stranded RNA induces inflammation via the NF-κB pathway and inflammasome activation in the outer root sheath cells of hair follicles

22 citations , March 2017 in “Scientific reports”

Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.

research 1410 Non-coding double stranded RNA induces retinoic acid synthesis and retinoid signaling to control regeneration

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.

research 944 Non-coding double stranded RNA induces retinoic acid synthesis and retinoid signaling to control regeneration

April 2019 in “Journal of Investigative Dermatology”

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

research Through the lens of hair follicle neogenesis, a new focus on mechanisms of skin regeneration after wounding

28 citations , October 2019 in “Seminars in Cell & Developmental Biology”

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

research Hypothesis: Wound‐induced TLR3 activation stimulates endogenous retinoic acid synthesis and signalling during regeneration

5 citations , March 2019 in “Experimental dermatology”

Activating TLR3 may help produce retinoic acid, important for tissue regeneration.

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