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GlossaryDrug Targets

specific molecules drugs interact with to produce therapeutic effects

Drug targets, also known as pharmacological targets or therapeutic targets, are specific molecules in the body, often proteins, that drugs interact with to produce a therapeutic effect. These targets can include enzymes, receptors, ion channels, or other proteins involved in disease processes. By binding to these targets, drugs can modify their activity, leading to changes in cellular function and ultimately improving health outcomes.

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Research

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research Drug Targeting to the Hair Follicles: A Cyclodextrin-Based Drug Delivery

32 citations , March 2009 in “AAPS PharmSciTech”

research Methodologies to Evaluate the Hair Follicle-Targeted Drug Delivery Provided by Nanoparticles

4 citations , July 2023 in “Pharmaceutics (Basel)”

Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.

research An update on nanocarriers for follicular-targeted drug delivery for androgenetic alopecia topical treatment

January 2025 in “Expert Opinion on Drug Delivery”

Nanocarriers could improve hair loss treatment but need more research for effectiveness and safety.

research Performance exploration of multi-gene panels of alopecia areata susceptibility and drug-binding targets

1 citations , March 2025 in “Frontiers in Physiology”

Methotrexate, resveratrol, and curcumin may help treat alopecia areata by targeting immune cells.

research Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders

14 citations , May 2022 in “Asian Journal of Pharmaceutical Sciences”

New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.

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Community Join

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community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

in Research/Science 114 upvotes 2 years ago

Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

community Is there any new drug that looks promising ?

in Research/Science 26 upvotes 2 years ago

The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

community September 2021 update from Dr. Kang-Yell Choi [Korean "cure"]

in Research/Science 31 upvotes 4 years ago

Dr. Kang-Yell Choi's company, CK Regeon, is developing a drug called KY19382 for hair regeneration, which involves creating fine wounds to activate stem cells. The drug is in the formulation development stage, targeting markets like the US and Korea.

community Who is the ideal target for PP405? Will it render hair trasplants obsolete?

in Transplants 2 upvotes 4 months ago

PP405 is being discussed as a potential treatment for hair loss, with uncertainty about its effectiveness compared to existing treatments like finasteride, dutasteride, and minoxidil. There is cautious optimism, but its impact on hair transplants remains unclear.

community Targeted Follicular Finasteride Delivery: A Low-Systemic Strategy

in Research/Science 15 upvotes 4 months ago

A peptide-based delivery system for finasteride shows promise in reducing systemic side effects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.

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