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GlossaryTargeted Drug Delivery

method of delivering medication directly to specific cells

Targeted Drug Delivery, also known as Targeted Therapy, is a method of delivering medication directly to specific cells or tissues, minimizing exposure to healthy cells and reducing side effects. This approach is particularly useful in treating diseases like cancer, where drugs can be directed to attack only cancerous cells, thereby improving treatment efficacy and patient outcomes.

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Research

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Dual-Drug Nanostructured Lipid Carriers of Spironolactone and 2-Deoxy-D-Ribose for Targeted Follicular Delivery in Androgenetic Alopecia

research Dual-drug nanostructured lipid carriers of spironolactone and 2-deoxy-D-ribose for targeted follicular delivery in androgenetic alopecia

May 2026 in “Drug Delivery and Translational Research”

Nanocarriers with spironolactone and 2-deoxy-D-ribose may improve hair loss treatment by targeting hair follicles directly.

research Multi-targeted synergy of Bacillus sp. TC5 fermentation products for transdermal drug delivery and hair regeneration

January 2026 in “Journal of Advanced Research”

Bacillus sp. TC5 products help hair regrowth and improve skin drug absorption.

research Niosomal Nanoformulations for Targeted Follicular Drug Delivery in Alopecia: An Integrative Review of Pathophysiology, Therapies, and Nanotechnology-Based Approaches

January 2026 in “Journal of advanced Biomedical and Pharmaceutical Sciences”

Niosomal cetirizine shows promise for better alopecia treatment by targeting hair follicles effectively.

research An update on nanocarriers for follicular-targeted drug delivery for androgenetic alopecia topical treatment

January 2025 in “Expert Opinion on Drug Delivery”

Nanocarriers could improve hair loss treatment but need more research for effectiveness and safety.

research Formulation and optimization of folate-bovine serum albumin-coated ethoniosomes of pterostilbene as a targeted drug delivery system for lung cancer: In vitro and in vivo demonstrations

20 citations , May 2023 in “Cancer Nanotechnology”

The new drug delivery system effectively targets lung cancer cells.

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Community Join

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community Targeted Follicular Finasteride Delivery: A Low-Systemic Strategy

in Research/Science 14 upvotes 3 months ago

A peptide-based delivery system for finasteride shows promise in reducing systemic side effects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 3 years ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Keratin microspheres - breakthrough

in Research/Science 14 upvotes 2 years ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community The story of RU58841/ PSK3841

in Research 622 upvotes 1 year ago

RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

community Expectations control for SCUBE3

in Research/Science 22 upvotes 2 years ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

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Learn

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learn Dutasteride

Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

learn Thymosin Beta 4

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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