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GlossaryEpithelial Proliferation

process where skin cells multiply and increase in number

Epithelial proliferation refers to the process by which epithelial cells, which form the outer layer of skin and line various organs and structures in the body, multiply and increase in number. This process is crucial for wound healing, tissue regeneration, and maintaining the integrity of barriers against pathogens. In the context of hair, epithelial proliferation is important for the growth and regeneration of hair follicles.

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Research

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research β1 Integrin Signaling Maintains Human Epithelial Progenitor Cell Survival In Situ and Controls Proliferation, Apoptosis and Migration of Their Progeny

20 citations , December 2013 in “PLoS ONE”

β1 integrin is essential for the survival, growth, and movement of human epithelial progenitor cells.

research 1458 EMT-inhibiting transcription factor Ovol2 regulates directional cell migration and proliferation in adult skin epithelia

April 2018 in “Journal of Investigative Dermatology”

Ovol2 is important for proper skin healing and hair growth.

research Peroxisome proliferator-activated receptor-γ signalling protects hair follicle stem cells from chemotherapy-induced apoptosis and epithelial–mesenchymal transition

19 citations , September 2021 in “British journal of dermatology/British journal of dermatology, Supplement”

Activating PPAR-γ signalling can protect hair follicle stem cells from damage caused by chemotherapy.

research An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation

30 citations , November 2018 in “EMBO Reports”

The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.

The Effects of Negative Pressure by External Tissue Expansion Device on Epithelial Cell Proliferation, Neo-Vascularization, and Hair Growth in a Porcine Model

research The Effects of Negative Pressure by External Tissue Expansion Device on Epithelial Cell Proliferation, Neo-Vascularization and Hair Growth in a Porcine Model

16 citations , April 2016 in “PLoS ONE”

Negative pressure treatment improved skin thickness, blood vessel growth, and hair growth.

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Community Join

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community Molecular mechanisms triggered by Micronedlling -- Intersting Publication to better understand Dermarolling

24 upvotes 7 years ago

This post and conversation are about the molecular mechanisms triggered by microneedling, specifically its effects on inflammation, tissue remodeling, epithelial proliferation, differentiation, and collagen synthesis. The discussion highlights the potential benefits of microneedling for hair loss treatment.

community abusing caffeine boosts DHT levels!

in Research/Science 1 upvotes 1 year ago

Caffeine intake may increase DHT levels, but its impact on hair loss is minimal compared to genetic factors. Excessive caffeine can cause health issues, and its effects on hair loss are not directly applicable to humans based on rat studies.

community Fresh off the press: Dutasteride may cause chronic infertility

in Research/Science 643 upvotes 1 year ago

Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

community SAFFLOWER OIL good alternative for Minoxidil?

in Treatment 1 upvotes 6 years ago

Safflower oil is suggested as an alternative to minoxidil for hair growth, with benefits including scalp conditioning and hair strength enhancement. Studies indicate it may also reverse scalp dermatitis, alopecia, and prevent premature grayness.

community Sandalore: a scientific homemade approch

19 upvotes 7 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

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Learn

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learn Epidermal Growth Factor

learn Beta Polypeptide

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Stem Cell Factor

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