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GlossaryEstrogen Receptor-Positive Breast Cancer

cancer type where cells grow due to estrogen binding

Estrogen Receptor-Positive Breast Cancer (ER+ Breast Cancer) is a type of breast cancer where the cancer cells have receptors that bind to the hormone estrogen. This binding promotes the growth of the cancer cells. Treatments often involve hormone therapies that block estrogen from attaching to these receptors, thereby slowing or stopping the cancer's growth.

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Research

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research The Safety of Local Hormonal Treatment for Vulvovaginal Atrophy in Women With Estrogen Receptor-positive Breast Cancer Who Are on Adjuvant Aromatase Inhibitor Therapy: Meta-analysis

18 citations , August 2019 in “Clinical breast cancer”

Local hormonal treatment for vulvovaginal atrophy is likely safe for women with estrogen receptor-positive breast cancer on aromatase inhibitors.

research Patient-Reported Outcomes From Phase III Neoadjuvant Systemic Trial Comparing Neoadjuvant Chemotherapy With Neoadjuvant Endocrine Therapy in Pre-Menopausal Patients With Estrogen Receptor-Positive and HER2-Negative, Lymph Node-Positive Breast Cancer

1 citations , July 2021 in “Frontiers in Oncology”

Neoadjuvant endocrine therapy led to a better future outlook than chemotherapy, with no major quality of life differences.

research A phase 1b study of chemo-immunotherapy with pegylated liposomal doxorubicin and Pembrolizumab in estrogen receptor positive metastatic breast cancer

June 2026 in “Cancer Research Communications”

The treatment combination is safe and effective for some patients with this type of breast cancer.

research Hair regrowth in endocrine therapy alopecia with dutasteride treatment in woman with estrogen positive breast cancer

March 2023 in “JAAD case reports”

Dutasteride and minoxidil helped regrow hair in a woman with breast cancer.

research Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells

8 citations , July 2022 in “International Journal of Molecular Sciences”

17β-estradiol lowers polyamine oxidase levels in breast cancer cells through estrogen receptor 2.

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community Treatment of Finasteride Induced Gynecomastia (Male breast tissue growth)

in Finasteride/Dutasteride 16 upvotes 5 years ago

Finasteride can cause gynecomastia, which may be reversible by stopping the drug and using selective estrogen receptor modulators (SERMs) like tamoxifen. Lifestyle changes such as weight loss and avoiding alcohol can also help, but surgery may be needed if the condition persists.

community if Post Finasteride Syndrome is real. Why is it only the negative effects and not positive have log term effect?

in Finasteride/Dutasteride 63 upvotes 3 months ago

Finasteride is used for hair loss, with mixed reports of no side effects and claims of long-term negative effects known as Post Finasteride Syndrome (PFS). The conversation debates the existence and causes of PFS, with differing opinions on whether it is psychological or real.

community Husband (35) is thinning on top, he doesn't know yet. Trying to research so he won't feel so lost or upset when I tell him. Help a girl out?

in Research/Science 160 upvotes 1 year ago

A woman is concerned about her husband's hair thinning and researches treatments like finasteride and minoxidil. He decides against medication due to potential side effects and plans to shave his head if necessary.

community What Works to Restore Hairloss for Cis-Males? Not Much

in Treatment 20 upvotes 5 years ago

Hair regrowth treatments for cis-males include Minoxidil, Finasteride, and RU58841. Estrogen and testosterone blockers can help restore hair loss but may not suit everyone.

community Kintor has announced the results for their human Phase I trials of GT20029

in Research/Science 258 upvotes 3 years ago

The conversation discusses the potential of a new hair loss treatment, GT20029, which may prevent hair loss by destroying androgen receptors on the scalp. Users express hope for the treatment's success and speculate on its usage routine, effectiveness, and possible side effects.

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