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Did you mean Extracellular Matrix Organization?

GlossaryExtracellular Matrix Organization

network of proteins and molecules outside cells is structured

Extracellular Matrix Organization (ECM Organization) refers to the process by which the network of proteins and other molecules outside cells is structured and maintained. This matrix provides structural support to tissues, influences cell behavior, and plays a crucial role in wound healing, tissue repair, and overall cellular function. Proper ECM organization is essential for maintaining healthy skin and hair, and disruptions in this process can contribute to conditions like alopecia.

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research Cultured dermal papilla cells of the rat vibrissa follicle. Proliferative activity, adhesion properties and reorganization of the extracellular matrix in vitro

27 citations , December 1997 in “Archives of Dermatological Research”

Rat dermal papilla cells have unique properties and interact differently with their environment compared to other skin cells.

research Cross-species comparative spatial transcriptomics of hair follicle-T cell interactions identifies conserved drivers of cutaneous lupus erythematosus skin disease and associated hair loss

July 2026 in “Nature Communications”

CXCR3+ T cells and B cells drive skin disease and hair loss in lupus, with potential targets identified for treatment.

research Dynamic interactions of lymphatic vessels at the hair follicle stem cell niche during hair regeneration

1 citations , February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)”

Lymphatic vessels are essential for hair follicle regeneration and growth.

Sox11 And Sox4 Drive The Reactivation Of An Embryonic Gene Program During Murine Wound Repair

research SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair

87 citations , September 2019 in “Nature Communications”

SOX11 and SOX4 help skin cells act like embryonic cells to heal wounds in mice.

research Endothelin-1 combined with extracellular matrix proteins promotes the adhesion and chemotaxis of amelanotic melanocytes from human hair follicles in vitro

11 citations , August 2006 in “Cell Biology International”

Endothelin-1 helps amelanotic melanocytes stick and move better on certain proteins.

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