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GlossaryFollicular Infundibulum

upper part of hair follicle where sebum exits

The follicular infundibulum is the upper part of a hair follicle, extending from the skin's surface down to the point where the sebaceous (oil) gland opens into the follicle. This region is crucial for the passage of sebum and dead skin cells to the skin's surface, and its blockage can lead to conditions like acne.

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Research

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research Microneedling dilates the follicular infundibulum and increases transfollicular absorption of liposomal sepia melanin

25 citations , June 2015 in “Clinical, Cosmetic and Investigational Dermatology”

Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.

Reflectance Confocal Microscopy Can Differentiate Dermoscopic White Dots of the Scalp Between Sweat Gland Ducts or Follicular Infundibulum

research Reflectance confocal microscopy can differentiate dermoscopic white dots of the scalp between sweat gland ducts or follicular infundibulum

20 citations , April 2011 in “British Journal of Dermatology”

Reflectance confocal microscopy can tell apart white dots on the scalp as either sweat gland ducts or hair follicle openings.

research Pilomatricoma can differentiate not only towards hair matrix and hair cortex, but also follicular infundibulum, outer root sheath and hair bulge

18 citations , March 2009 in “Experimental Dermatology”

Pilomatricoma can develop into various hair-related structures.

research Tumors of the follicular infundibulum

June 2019

Benign tumors from hair follicles can look like other skin cancers but have distinct features under dermoscopy.

research The changes in the expression levels of follicular markers in keratoacanthoma depend on the stage: keratoacanthoma is a follicular neoplasm exhibiting infundibular/isthmic differentiation without expression of CK15

28 citations , February 2014 in “Journal of Cutaneous Pathology”

Keratoacanthoma changes as it grows, showing different hair follicle characteristics at each stage.

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community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 3 years ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community Quote from Pelage (PP-405) Spokesperson...

in Research/Science 121 upvotes 9 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Information regarding Follicusan DP?

in Product 3 upvotes 2 years ago

Follicusan DP is discussed as a potential alternative to Minoxidil without side effects, but information is scarce. It is noted to be of German origin and details on its mechanism are limited.

community Targeted Follicular Finasteride Delivery: A Low-Systemic Strategy

in Research/Science 15 upvotes 4 months ago

A peptide-based delivery system for finasteride shows promise in reducing systemic side effects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.

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