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Did you mean Follicular Keratinization?

GlossaryFollicular Keratinization

process where hair follicle cells produce and harden keratin

Follicular keratinization is the process by which cells in the hair follicle produce keratin, a protein that forms the structure of hair. This process involves the hardening and flattening of these cells as they move up the follicle, eventually forming the hair shaft. Proper keratinization is essential for healthy hair growth, while abnormalities in this process can lead to hair disorders.

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Research

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research Hair sheath keratins in follicular tumors. (5). Identification of hair sheath keratins in keratoacanthoma; Histopathological hair sheath structures in the tumor and their significance as differential histopathological criteria from squamous cell carcinoma.

January 1990 in “The Nishinihon Journal of Dermatology”

Follicular structures help differentiate keratoacanthoma from squamous cell carcinoma.

research Induction of Hair Keratins Expression by an Annurca Apple-Based Nutraceutical Formulation in Human Follicular Cells

13 citations , December 2019 in “Nutrients”

An apple-based supplement was found to stimulate hair protein production, which may help with hair growth.

research Angora Mouse Mutation: Altered Hair Cycle, Follicular Dystrophy, Phenotypic Maintenance of Skin Grafts, and Changes in Keratin Expression

69 citations , May 1997 in “Veterinary Pathology”

The angora mouse mutation causes long hair and hair defects due to a gene deletion.

Dendrobium Officinale Polysaccharide Improves Hair Regrowth in Androgenetic Alopecia Mice and Is Associated with Coordinated Changes in Local Steroid Metabolism, ESR1 Activation, and Keratin-Related Follicular Responses

research Dendrobium officinale polysaccharide improves hair regrowth in androgenetic alopecia mice and is associated with coordinated changes in local steroid metabolism, ESR1 activation, and keratin-related follicular responses

May 2026 in “Frontiers in Pharmacology”

Dendrobium officinale polysaccharide helps hair regrowth in hair loss mice by affecting local steroid metabolism and hair follicle responses.

research Severe follicular hyperplasia and spontaneous papilloma formation in transgenic mice expressing theneu oncogene under the control of the bovine keratin 5 promoter

47 citations , January 1998 in “Molecular Carcinogenesis”

ErbB2 signaling is crucial for skin cell growth and cancer development in mice.

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Community Join

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community a new supplement just released

11 upvotes 8 years ago

A dermatologist recommended a new supplement containing annurca apple, which reportedly doubles hair density and increases keratin after 60 days, to be used with finasteride. Some users are skeptical, considering it potentially ineffective or a marketing ploy, while others are open to trying it if it proves effective and affordable.

community What supplements or extra dtuff do you guys do for your hair?

in Product 2 upvotes 1 year ago

OP uses multivitamins, collagen, biotin, keratin, omega-3, satin bonnet, dandruff shampoo, oil moisturizer, and sun exposure for hair care. Users suggest adding antioxidants, probiotics, pumpkin seed oil, vitamin D, iron, and dermastamping.

community Minoxidil Response Bottlenecks: Why Sulfation and Transport Matter (And Where Tretinoin Fits In)

in Research 461 upvotes 1 year ago

Minoxidil's effectiveness is limited by the need for sulfation and proper transport to hair follicles, with tretinoin potentially enhancing its effects by promoting enzyme activity and keratinocyte differentiation. Tretinoin may improve minoxidil's response by boosting the expression of necessary enzymes and transporters.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community [Discussion] Trichoscopy in sudden-onset AGA: Pathology and reversibility of "Yellow Dots" without 5AR-inhibitors?

in Research/Science 5 upvotes 4 months ago

Hair loss treatments discussed include microneedling, minoxidil, tretinoin, finasteride, dutasteride, pumpkin seeds, saw palmetto, and scalp massage. The consensus is that finasteride or dutasteride is necessary for significant regrowth, while other methods may only slow hair loss.

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Learn

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learn Epidermal Growth Factor

learn Thymosin Beta 4

learn Overview

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