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Did you mean Hair Shaft Disorders?

GlossaryHair Shaft Disorders

conditions affecting hair structure, causing brittleness and breakage

Hair Shaft Disorders are conditions that affect the structure and integrity of the hair shaft, leading to issues like brittleness, breakage, and abnormal hair texture. These disorders can be genetic or acquired and often result from defects in the proteins that make up the hair, such as keratin, or from external factors like excessive heat or chemical treatments.

Related Terms

Research

5 / 1000+ results

research The genetics of hair shaft disorders

59 citations , June 2008 in “Journal of The American Academy of Dermatology”

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

research Hair shaft disorders in a child with loose anagen syndrome and uncombable hair: Clues to an underlying genetic disorder

July 2026 in “Indian Journal of Dermatology Venereology and Leprology”

research Common genetic hair shaft abnormalities may be visualized by light and electron microscope

January 2019 in “Global Dermatology”

Genetic hair shaft abnormalities can be seen with microscopes and often affect scalp hair.

research Prognosis and Management of Congenital Hair Shaft Disorders with Fragility—Part I

33 citations , June 2016 in “Pediatric Dermatology”

Some congenital hair disorders improve in childhood or with treatments like minoxidil and retinoids, while others like Netherton syndrome and trichothiodystrophy have a poor prognosis.

research Genetic Hair Disorders: A Review

26 citations , July 2019 in “Dermatology and Therapy”

The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

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Community Join

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community How does hair loss and recovery work?

in Chat 12 upvotes 1 year ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

in Chat 138 upvotes 10 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

community Hair loss research is a money grab

in Chat 227 upvotes 8 months ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 2 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

community Ray Peat: Testosterone Isn’t the Culprit, Prolactin and Cortisol Drive Hair Loss (2016)

in Research/Science 110 upvotes 9 months ago

Prolactin and cortisol are identified as key factors in hair loss, with stress hormones impacting hair shedding. Finasteride and minoxidil are effective treatments, while DHT's role and individual sensitivity are significant factors.

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