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GlossaryHair Shaft Alterations

changes in hair's structure affecting thickness, texture, or strength

Hair Shaft Alterations refer to changes or abnormalities in the structure of the hair shaft, which is the visible part of the hair that extends above the scalp. These alterations can include variations in thickness, texture, strength, and overall appearance, and can be caused by genetic factors, environmental damage, or underlying health conditions. For professionals, understanding these alterations is crucial for diagnosing hair disorders and recommending appropriate treatments.

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Research

5 / 1000+ results

research Alterations in Hair Follicle Morphology and Hair Shaft Production After Follicular Unit Transplantation

8 citations , February 2016 in “The American Journal of Dermatopathology”

Hair transplants can make hair follicles larger and hair shafts thicker.

research Adverse reaction to isotretinoin: alteration of the hair shaft structure

January 2022 in “Surgical & Cosmetic Dermatology”

Isotretinoin can rarely cause hair to grow curly.

research Hair cosmetic alterations

September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.

research Hair abnormalities and neurological disease

September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Hair changes could indicate neurological diseases and help monitor treatment.

research Use of Low-Cost Videomicroscopy versus Standard Videodermatoscopy in Trichoscopy: A Controlled, Blinded Noninferiority Trial

10 citations , January 2015 in “Skin appendage disorders”

Low-cost videomicroscopes are not as reliable as standard videodermatoscopes for scalp examination due to lower image quality.

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Community Join

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community Reminder: NURTURE those dormant hair follicles for as long as you can until PP405 comes out in 2028-2030

in Treatment 191 upvotes 8 months ago

PP405 is anticipated as a future treatment for dormant hair follicles, but its effectiveness and safety are uncertain. Current treatments include oral minoxidil and microneedling, with some avoiding finasteride due to side effects.

community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

in Treatment 90 upvotes 6 years ago

Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

community Results are in for my experiment with Creatine/Fin

in Finasteride 134 upvotes 6 years ago

Creatine use with finasteride increased DHT levels, possibly affecting hair loss. The user plans to reduce creatine to stabilize DHT and hair shedding.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 410 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community FDA Policy Shift Explained: What It Actually Means for PP405, VDPHL-01, Breezula and Hair Loss Drug Timelines

in Research/Science 42 upvotes 5 months ago

The FDA policy change may speed up approval for hair loss drugs like PP405, VDPHL-01, and Breezula by potentially eliminating the need for a second confirmatory Phase 3 trial. Approval timelines could be as early as 2028 for some treatments if Phase 3 results are strong.

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