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GlossaryHair Follicle Dynamics

cyclical process of hair growth, rest, and shedding

Hair Follicle Dynamics refers to the cyclical process of growth, rest, and shedding that hair follicles undergo. This cycle includes three main phases: anagen (growth phase), catagen (transitional phase), and telogen (resting phase). Understanding these dynamics is crucial for diagnosing and treating hair loss conditions like alopecia.

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Research

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research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics

38 citations , June 2019 in “International Journal of Molecular Sciences”

Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.

research Alterations in Hair Follicle Dynamics in Women

26 citations , January 2013 in “BioMed Research International”

Hormonal changes after childbirth and menopause can lead to women's hair loss and facial hair growth, with a need for better treatments.

research Analysing the dynamics of a model for alopecia areata as an autoimmune disorder of hair follicle cycling

11 citations , June 2017 in “Mathematical Medicine and Biology A Journal of the IMA”

The model helps understand and improve treatments for alopecia areata by simulating hair growth and immune cell interactions.

research Stem cell dynamics in the hair follicle niche

135 citations , December 2013 in “Seminars in Cell & Developmental Biology”

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

research Linking chromatin dynamics, cell fate plasticity, and tissue homeostasis in adult mouse hair follicle stem cells

3 citations , July 2017 in “Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model”

Mouse hair follicle stem cells have a flexible chromatin state that supports skin health and hair growth.

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Community Join

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community If we can clone a sheep why we can't cure baldness till now

in Research/Science 181 upvotes 10 months ago

Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 3 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.