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GlossaryHair Follicle Homeostasis

balanced state of hair follicles cycling through growth and rest

Hair follicle homeostasis refers to the balanced state of hair follicles, where they cycle through growth, rest, and shedding phases in a regulated manner. This balance is crucial for maintaining healthy hair density and preventing conditions like alopecia, where hair loss occurs due to disruptions in this cycle.

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Research

5 / 1000+ results

research EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair

354 citations , February 2011 in “Genes & Development”

EZH1 and EZH2 are crucial for healthy hair growth and skin repair.

research Ligand-Independent Actions of the Vitamin D Receptor Maintain Hair Follicle Homeostasis

144 citations , December 2004 in “Molecular Endocrinology”

The vitamin D receptor is essential for normal hair growth, even without its usual binding.

The Critical Roles of Serum/Glucocorticoid-Regulated Kinase 3 (SGK3) in Hair Follicle Morphogenesis and Homeostasis

research The Critical Roles of Serum/Glucocorticoid-Regulated Kinase 3 (SGK3) in the Hair Follicle Morphogenesis and Homeostasis

9 citations , April 2006 in “American Journal of Pathology”

SGK3 is essential for proper hair growth and health.

research Paxbp1 is Indispensable for the Maintenance of Hair Follicle Homeostasis

May 2025 in “Acta Dermato Venereologica”

The Paxbp1 gene is crucial for healthy hair follicles.

The G-Protein Coupled Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis

research The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis

April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

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Community Join

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community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

in Chat 55 upvotes 2 years ago

The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

in Satire 353 upvotes 3 years ago

The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community The no BS guide to saving your hair without finasteride (improvement in 90% of patients in the study) with a low side effect profile or improvement in 100% of patients but a higher side effect profile and increased dosage. The future is here?

in Minoxidil 92 upvotes 6 years ago

Hair loss treatments, specifically the use of oral minoxidil in combination with micro-needling. Oral minoxidil has been found to improve hair density in 90% of patients with a low side effect profile, but using 5mg per day can result in higher side effects including hypertrichosis and edema. Other treatments mentioned include finasteride and RU58841.

community Circadian rhythm disruption and its potential impact on hair growth cycles

in Technology 7 upvotes 3 months ago

Poor sleep quality may affect hair growth cycles by disrupting the body's natural clock and stress hormones. The focus should be on improving sleep to support overall health, including hair growth, rather than relying solely on treatments like Minoxidil, finasteride, or RU58841.

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Learn

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learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

learn Stem Cell Factor

learn Beta Polypeptide

learn Epidermal Growth Factor

learn Latanoprost

glaucoma medication with hair follicle stimulant effects

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Clinics

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All 37 clinic results →

Experts

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