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GlossaryHair Follicle Physiology

study of hair follicle function and growth cycles

Hair Follicle Physiology refers to the study of how hair follicles function and grow. It involves understanding the life cycle of hair, including the growth (anagen), regression (catagen), and resting (telogen) phases, as well as the cellular and molecular mechanisms that regulate these processes. This knowledge is crucial for addressing conditions like alopecia (hair loss) and developing treatments for hair growth.

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Research

5 / 1000+ results

research The Effect of Parathyroid Hormones on Hair Follicle Physiology: Implications for Treatment of Chemotherapy-Induced Alopecia

15 citations , January 2015 in “Skin Pharmacology and Physiology”

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

research 4 Hair Follicle Physiology and Mechanisms of Hair Disorders

October 2022 in “Hair Transplantation”

Hair disorders are caused by genetics, environment, hormones, or inflammation, and treatments focus on normalizing hair growth and density.

Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice

research Skin physiology in microgravity: a 3-month stay aboard ISS induces dermal atrophy and affects cutaneous muscle and hair follicles cycling in mice

48 citations , May 2015 in “NPJ microgravity”

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration

research Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration

305 citations , June 2012 in “Nature”

Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.

PPAR-γ Signaling as a Key Mediator of Human Hair Follicle Physiology and Pathology

research PPAR‐γ signalling as a key mediator of human hair follicle physiology and pathology

24 citations , November 2019 in “Experimental Dermatology”

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

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Community Join

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community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

in Research/Science 126 upvotes 3 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

community ladies and gentlmen, vitamin E is your hair follicles second best friend

in Treatment 51 upvotes 3 years ago

Vitamin E is suggested as beneficial for hair follicles. Some users question the dosage and effectiveness, while others share positive experiences with vitamins.

community Table of the relationship between physical exercise and the regeneration of the deminiaturized hair follicle

in Research/Science 45 upvotes 1 year ago

Exercise, especially leg workouts, combined with finasteride and minoxidil, may enhance hair regrowth. Cold exposure, like cold showers, might further boost results.

community The end of balding: We may have just found the secret to hair regrowth

in Technology 680 upvotes 1 year ago

MCL-1 is important for hair follicle stem cell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 2 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

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Learn

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learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Estradiol

an estrogen promoting hair regrowth more commonly used in women

learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

learn PP405

mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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Clinics

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All 33 clinic results →

Experts

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