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research Fibroblasts and endothelial cells interplay drives hypertrophic scar formation: Insights from in vitro and in vivo models

21 citations , December 2023 in “Bioengineering & Translational Medicine”

Fibroblast and endothelial cell interactions are crucial in forming hypertrophic scars.

research Self-Organizing 3D Dermal Papilla Cell Spheroids Yield Therapeutic Extracellular Vesicles that Target Hypertrophic Scar Regression via the miR-26a-5p/CCNE2 Axis

July 2025 in “Burns & Trauma”

3D cell spheroids can help reduce scars by delivering therapeutic vesicles.

Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Regeneration After Facial Nerve Injury

research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury

6 citations , February 2022 in “The journal of neuroscience/The Journal of neuroscience”

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

research A regulatory perspective on pharmacokinetic/pharmacodynamic modelling

18 citations , June 1999 in “Statistical Methods in Medical Research”

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Scaly Papular Lesions: Treatment and Clinical Course of Actinic Keratosis

research Scaly Papular Lesions

January 2018 in “Elsevier eBooks”

Topical imiquimod is as effective as 5-fluorouracil for treating actinic keratosis, with about a 5% risk of it turning into squamous cell carcinoma.

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Community Join

5 / 63 results

community Just to show you the superiority of dutasteride over finasteride (it's huge)

in Research/Science 58 upvotes 2 years ago

Dutasteride is shown to be significantly more effective than finasteride for treating male androgenic alopecia. Users discuss the difficulty of obtaining dutasteride in some countries and share personal experiences with its effectiveness and side effects.

community Male pattern baldness is not cosmetic.

in Chat 223 upvotes 8 months ago

Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

community What's "wrong" with oral minoxidil, exactly?

in Minoxidil 173 upvotes 1 year ago

Oral minoxidil can boost hair growth but may cause side effects like heart palpitations and increased body hair. Many prefer topical minoxidil due to fewer side effects.

community Does losing your hair make you hit the gym ?

in Satire 3 years ago

How some people start going to the gym when they begin to lose their hair, as well as discussing various treatments (Finasteride, Minoxidil and Dermarolling) for hair loss.

community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

in Research/Science 129 upvotes 2 years ago

The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

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