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research Enhanced ex vivo skin retention of bicalutamide using a nano-in-micro composite: Drug-loaded lipid vesicles in a dissolving microarray patch

April 2025 in “European Journal of Pharmaceutics and Biopharmaceutics”

The new drug delivery system improves bicalutamide skin retention for better treatment of hair loss.

research Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

5 citations , January 2017 in “Chalmers Publication Library (Chalmers University of Technology)”

Cubosomes enhance antimicrobial peptide stability and effectiveness.

research Treatment of alopecia areata in the DEBR model using Cyclosporin A lipid vesicles.

54 citations , December 2004 in “PubMed”

Cyclosporin A vesicles effectively regrow hair and reduce inflammation in alopecia areata.

research Advances in nanomaterial-mediated CRISPR/Cas delivery: from lipid nanoparticles to vesicle-derived systems

1 citations , January 2026 in “Frontiers in Bioengineering and Biotechnology”

Ionizable lipid nanoparticles are the best for delivering gene-editing therapies.

research Function and interactions of the Ysc84/SH3yl1 family of actin- and lipid-binding proteins

6 citations , January 2015 in “Biochemical Society Transactions”

The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.

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Community Join

5 / 171 results

community Does melatonin dissolve in isopropyl alcohol

in Technology 7 upvotes 3 years ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community Has anyone tried Exosomes from Musely or somewhere else?

in Hair Systems 10 upvotes 1 year ago

Exosomes from Musely are being discussed as a topical hair loss treatment containing ingredients like latanoprost, caffeine, cetirizine, melatonin, vitamin D3, vitamin E, and biotin. Users are curious about its effectiveness and potential side effects, noting it may take 4-6 months to see results.

community Switching RU vehicle due to scalp irritation – anyone tried low-EtOH + squalane / emu oil?

in Treatment 2 upvotes 8 months ago

The user is experiencing scalp irritation from using RU58841 with a 70% ethanol and 30% propylene glycol vehicle and is considering switching to a less irritating vehicle, such as 30% ethanol with 70% squalane or emu oil. They are seeking feedback on the effectiveness and irritation levels of these alternative carriers.

community Topical fin - why are people still using alcohol carriers when liposomal is proven to be better?

in Treatment 7 upvotes 1 year ago

Liposomal carriers for topical finasteride offer better targeting, reduced side effects, and less irritation compared to alcohol-based solutions, but availability and cost may limit their use. Minoxidil can dissolve in liposomal carriers, enhancing delivery and stability.

community My progress with various products and without oral fin or oral dut on 17 months

in Progress Pictures 62 upvotes 1 year ago

The user shared their hair loss treatment progress using topical products like exosomes, fluridil, Kx826, and topical dutasteride, avoiding oral finasteride and dutasteride due to side effects. They found exosomes from Creative Biolabs most effective and also used topical probiotics, noting improvements without significant side effects.

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