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research Gain‐of‐function variants in the ODC1 gene cause a syndromic neurodevelopmental disorder associated with macrocephaly, alopecia, dysmorphic features, and neuroimaging abnormalities

28 citations , November 2018 in “American Journal of Medical Genetics Part A”

ODC1 gene mutations cause a neurodevelopmental disorder with large head size, hair loss, and facial abnormalities.

research Comparative Studies on Polyamine Levels in Plasma and Urine of Androgenic Alopecia Patients Treated with Finasteride for a Period of Three Years

January 2020 in “International Journal of Applied Biology and P”

Finasteride treatment for three years changes certain polyamine levels in the blood but not in urine.

research Distribution of polyamines may be altered in different scalp regions of patients with hair loss

3 citations , July 2019 in “Experimental Dermatology”

Hair loss patients may have different polyamine levels in various scalp areas.

research Drug Repurposing Patent Applications July–September 2025

January 2025 in “Drug repurposing”

New drug uses show promise but need more research.

research Bachmann–Bupp syndrome and treatment

July 2023 in “Developmental medicine and child neurology/Developmental medicine & child neurology”

DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.

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learn ACETYL TETRAPEPTIDE-2

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community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

in Research/Science 26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community Clinical Trial: N-Acetyl-Cysteine for Treatment of AGA in Men

in Treatment 5 upvotes 5 years ago

N-Acetyl-Cysteine (NAC) is being explored for treating hair loss, but users report mixed results. Some also mention using Quercetin and Resveratrol without significant hair improvement.

community Minokem-N cotains hydrocortisone?

in Minoxidil 2 upvotes 1 year ago

Minokem-N's composition is unclear, with concerns about unlisted hydrocortisone. Users discuss alternatives like AloATM, which lacks soothing agents, and the challenges of verifying ingredients.

community Before n after… #OralMinfortheWin

in Progress Pictures 71 upvotes 3 years ago

The user "mallanboy" shared their experience with using 0.5mg Dutasteride once a week, 0.5mg Finasteride every day, and 2.5mg Minoxidil every day for hair loss. They mentioned that their hairline has slightly improved and their hair density has increased after switching from topical minoxidil to oral minoxidil after 8 months. They hope to maintain their results until they are 30 years old for a hair transplant.

community Nanoxidil Spectral.DNC-n 60ml.

in Treatment 1 upvotes 2 years ago

A user recently started using nanoxidil 5% for hair loss, particularly on the hairline, and is seeking feedback or experiences from others. The conversation focuses on the effectiveness of nanoxidil.

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