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GlossaryNerve Fibers

long extensions of neurons transmitting electrical impulses

Nerve fibers, also known as nerve filaments or neural fibers, are the long, thread-like extensions of nerve cells (neurons) that transmit electrical impulses throughout the body. These fibers are essential for communication within the nervous system, enabling sensations, movements, and various bodily functions by carrying signals between the brain, spinal cord, and other parts of the body.

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Research

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research A simple immunofluorescence technique for simultaneous visualization of mast cells and nerve fibers reveals selectivity and hair cycle - dependent changes in mast cell - nerve fiber contacts in murine skin

109 citations , April 1997 in “Archives of Dermatological Research”

Mast cell and nerve fiber interactions in mouse skin change with the hair cycle.

research Fibre optic confocal imaging (FOCI) of keratinocytes, blood vessels and nerves in hairless mouse skin in vivo

36 citations , February 1998 in “Journal of Anatomy”

Fibre optic confocal imaging can visualize skin layers, blood vessels, and nerves in live mice.

research Changes in intraepidermal nerve fiber and Langerhans cell densities in the plantar skin of rats after mercuric chloride exposure

6 citations , November 2017 in “Journal of the Peripheral Nervous System”

Mercury exposure damages small nerve fibers in rats' skin.

research 509 Using the human iPSCs-derived sensory neurons re-innervated skin ex vivo model to investigate mast cell-nerve fiber cross-talk in solar elastosis

November 2024 in “Journal of Investigative Dermatology”

Nerve fibers may worsen mast cell activity, leading to abnormal elastic fiber buildup from sun exposure.

research Characteristic intraepidermal nerve fibre endings of the intervibrissal fur in the mystacial pad of the rat: morphological details revealed by intravital methylene blue staining and the zinc iodide-osmium tetroxide technique

5 citations , July 1999 in “Journal of Anatomy”

Methylene blue staining effectively highlights detailed nerve structures in rat fur.

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community I Guess balding is cured so should we close subreddit and move to hairstyling photos 😁 Botox-like nerve blocking reveals potential way to fully regenerate skin without scarring

in Technology 4 months ago

Baldness is difficult to cure because current treatments like finasteride, dutasteride, and minoxidil only prevent hair shedding, and new developments are mostly ineffective. Botox shows potential in aiding skin regeneration and hair growth, but maintenance therapy with treatments like dutasteride and minoxidil may still be necessary.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 3 years ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community Is itching related to hair loss?

in Treatment 54 upvotes 3 years ago

Hair loss, which is sometimes accompanied by itching. Treatments discussed include Minoxidil, finasteride, RU58841 and ketocazole shampoo.

community Hair Transplant Issues & Hair Loss Medication Side Effects - Similar Experiences

in Basic Questions 187 upvotes 2 months ago

The user experienced long-term pain after an FUE hair transplant and is considering Kenacort injections for relief. They also reported brain fog, dizziness, and anxiety after stopping minoxidil and finasteride, and are currently using PRP, microneedling, and rosemary oil for hair maintenance.

community How bad is the shed phase really?

in Chat 6 upvotes 3 months ago

The shed phase from using finasteride and minoxidil can vary, with some experiencing noticeable hair loss and others having minimal shedding. Despite initial shedding, many users report eventual hair regrowth and improvement, making the treatment worthwhile.

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