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GlossaryNeutrophilic Dermatosis

group of skin disorders with excess neutrophils causing lesions

Neutrophilic dermatosis is a group of skin disorders characterized by the accumulation of neutrophils, a type of white blood cell, in the skin. These conditions often present with red, swollen, and sometimes painful lesions or pustules, and can be associated with systemic diseases like inflammatory bowel disease or certain types of leukemia.

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research Erosive pustular dermatosis of the scalp: A neutrophilic folliculitis within the spectrum of neutrophilic dermatoses

25 citations , October 2018 in “Journal of The American Academy of Dermatology”

Erosive pustular dermatosis of the scalp is a type of skin inflammation often confused with other conditions, requiring continuous treatment.

Review of Aseptic Neutrophilic Dermatoses

research REVIEW OF SO-CALLED ASEPTIC NEUTROPHILIC DERMATOSES

17 citations , August 1983 in “Australasian Journal of Dermatology”

The review says skin conditions with sterile pustules need more research for better treatments.

research 178 Neutrophil elastase is critical in linear IgA bullous dermatosis in mice

April 2023 in “Journal of Investigative Dermatology”

CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.

research Erosive pustular dermatosis of the scalp and multiple sclerosis: just a coincidence?

2 citations , July 2022 in “Dermatology Reports”

EPDS and MS might share an immune-related cause.

Incidence and Hemato-Biochemical Alterations in Dermatoses Associated with Hypothyroidism in Dogs

research Incidence and haemato-biochemical alterations in dermatoses associated with hypothyroidism in dogs

February 2026 in “International Journal of Advanced Biochemistry Research”

Hypothyroidism-related skin issues in dogs are most common in older male Labradors, causing hair loss, slow heart rate, and obesity.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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