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    Did you mean Peripilar Sign?
    GlossaryPeripilar Sign

    small pigmented spots around hair follicles indicating inflammation

    The Peripilar Sign refers to a specific clinical feature observed in some cases of hair loss, particularly in conditions like alopecia areata. It is characterized by the presence of small, pigmented spots or halos around the hair follicles, which can be seen under dermoscopy. This sign indicates inflammation around the hair follicles and can help dermatologists diagnose and assess the severity of hair loss conditions.

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      community The MPB itch aka DHT itch is very real.

      in Chat  9 upvotes 3 years ago
      Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  53 upvotes 1 week ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community Little hairs on temples, is it a good sign?

      in Is this regrowth?  425 upvotes 10 months ago
      The conversation discusses hair regrowth, with users sharing experiences and advice on using finasteride, minoxidil, and dermarolling to stimulate hair growth. Many users report seeing small hairs, which they consider a positive sign, though opinions vary on whether these hairs will develop into thicker, terminal hairs.

      community Thinking about signing up for the setipiprant clinical trials

       5 upvotes 8 years ago
      The conversation discusses hair loss treatments, with the original poster considering joining a clinical trial for setipiprant after experiencing side effects from finasteride and disinterest in minoxidil. Some users express skepticism about setipiprant's effectiveness, while others encourage participation in the trial for potential benefits.