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    Did you mean Piperine?
    GlossaryPiperine

    alkaloid that gives black pepper its spiciness

    Piperine is an alkaloid responsible for the pungency of black pepper and long pepper. It enhances the bioavailability of various nutrients and drugs by inhibiting certain enzymes involved in their metabolism, making it a valuable compound in both culinary and medicinal contexts.

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      Can liver problems be associated with response to the oral minoxidil?

      community Can liver problems be associated with response to the oral minoxidil?

      in Research  147 upvotes 4 days ago
      Liver problems may reduce the effectiveness of oral minoxidil due to impaired SULT1A1 enzyme activity, which is crucial for converting minoxidil to its active form. This reduction in enzyme function can significantly decrease the drug's effectiveness in promoting hair growth.

      community My Research Compilation on Nutrafol

      in Research/Science  11 upvotes 3 years ago
      Nutrafol, a hair loss supplement, has limited and potentially biased research, with one study showing a 10% increase in hair count for women after 6 months but no significant results for men. The user concludes that cheaper, well-studied options like minoxidil may be more effective, especially for men, given the lack of evidence supporting Nutrafol.

      community Dim: high estradiol levels what to do

      in Chat  8 upvotes 1 year ago
      A user is experiencing facial bloating from low-dose topical finasteride due to high estradiol levels and is seeking advice on using DIM to manage this issue, including dosage and brand recommendations.