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GlossaryProstate

small gland in males producing seminal fluid for sperm transport

The prostate is a small, walnut-sized gland in males located just below the bladder and in front of the rectum. It produces seminal fluid, which nourishes and transports sperm during ejaculation. This gland plays a crucial role in male reproductive health, and its enlargement or dysfunction can lead to conditions such as benign prostatic hyperplasia (BPH) or prostate cancer.

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Products matching "prostate"

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Research

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research 2022 Update on Prostate Cancer Epidemiology and Risk Factors—A Systematic Review

710 citations , May 2023 in “European Urology”

Prostate cancer is common, but risk can be reduced by avoiding smoking, unhealthy diet, inactivity, certain medications, and risky jobs.

Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

402 citations , August 2011 in “Cancer research”

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

research DIHYDROTESTOSTERONE AND THE PROSTATE: THE SCIENTIFIC RATIONALE FOR 5α-REDUCTASE INHIBITORS IN THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA

235 citations , September 2004 in “The Journal of urology/The journal of urology”

Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.

research ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

224 citations , February 2013 in “The Journal of clinical investigation/The journal of clinical investigation”

ERG increases SOX9, promoting prostate cancer growth and invasion.

research Species Differences in Prostatic Steroid 5α-Reductases of Rat, Dog, and Human

193 citations , August 1985 in “Endocrinology”

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

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Community Join

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community Fin effects on prostate sensation for MSM

in Finasteride/Dutasteride 5 upvotes 4 years ago

Finasteride may affect prostate sensation and size, with some users reporting easier urination. Concerns exist about prostate shrinkage even at lower doses.

community Finasteride weird side effects: slight discomfort in lower abdomen/bladder/prostate

in Finasteride 135 upvotes 1 year ago

The user experienced bladder and prostate discomfort after taking finasteride and stopped the medication, but symptoms returned upon resuming at a lower dose. The doctor suggested trying dutasteride as an alternative.

community Evolution theory: AGA is your body trying to reduce the risk of prostate cancer by exposing your scalp to more UV

in Research/Science 8 months ago

Androgenic alopecia (AGA) might have evolved to reduce prostate cancer risk by increasing UV exposure to the scalp, but this theory is debated. Treatments like minoxidil and finasteride are used for AGA, though the exact causes and evolutionary reasons for hair loss are unclear.