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GlossaryProstate Cancer

cancer that develops in the prostate gland in men

Prostate cancer, also known as prostatic carcinoma, is a type of cancer that occurs in the prostate gland, which is a small walnut-shaped gland in men that produces seminal fluid. It is one of the most common types of cancer in men and can range from slow-growing tumors that may not cause significant harm to aggressive forms that can spread quickly to other parts of the body. Early detection through screening methods like PSA (Prostate-Specific Antigen) tests and digital rectal exams can improve treatment outcomes.

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Tracking 1 products like 14 Topical Finasteride & Minoxidil Spray from by companies like Hims. View product »

Research

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research 2022 Update on Prostate Cancer Epidemiology and Risk Factors—A Systematic Review

710 citations , May 2023 in “European Urology”

Prostate cancer is common, but risk can be reduced by avoiding smoking, unhealthy diet, inactivity, certain medications, and risky jobs.

Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

402 citations , August 2011 in “Cancer research”

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

research ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer

224 citations , February 2013 in “The Journal of clinical investigation/The journal of clinical investigation”

ERG increases SOX9, promoting prostate cancer growth and invasion.

research A Review on the Clinical Utility of PSA in Cancer Prostate

154 citations , March 2012 in “Indian Journal of Surgical Oncology”

PSA is best for detecting prostate cancer recurrence and evaluating treatment response.

research Understanding the Epidemiology, Natural History, and Key Pathways Involved in Prostate Cancer

153 citations , April 2009 in “Urology”

Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.

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Community Join

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community Evolution theory: AGA is your body trying to reduce the risk of prostate cancer by exposing your scalp to more UV

in Research/Science 8 months ago

Androgenic alopecia (AGA) might have evolved to reduce prostate cancer risk by increasing UV exposure to the scalp, but this theory is debated. Treatments like minoxidil and finasteride are used for AGA, though the exact causes and evolutionary reasons for hair loss are unclear.

community Fin effects on prostate sensation for MSM

in Finasteride/Dutasteride 4 upvotes 4 years ago

Finasteride may affect prostate sensation and size, with some users reporting easier urination. Concerns exist about prostate shrinkage even at lower doses.

community Should I Seek a Second Opinion on Finasteride at 22?

in Basic Questions 114 upvotes 2 weeks ago

The user is concerned about hair loss and has been using finasteride and minoxidil. The doctor refused to prescribe finasteride due to a perceived increased risk of prostate cancer, prompting the user to consider seeking another doctor's opinion.

community Fresh off the press: Dutasteride may cause chronic infertility

in Research/Science 643 upvotes 1 year ago

Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

community Nutrafol backed by Science to reverse male balding?

in Research/Science 1 upvotes 1 year ago

Nutrafol helps improve hair thickness and hairline but may have potential health risks like liver damage and increased prostate cancer risk. The user plans to continue Nutrafol at a lower dosage while managing seborrheic dermatitis and considers future use of topical finasteride, minoxidil, rosemary oil, and microneedling.

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