The Patient Journey In Prurigo Nodularis: What Lies Ahead

Prurigo nodularis (PN) is a chronic skin disorder marked by intensely itchy nodules that significantly impact patients' quality of life. Although recent advances have been made in understanding its neuroimmune pathogenesis and developing targeted biologics like dupilumab and nemolizumab, PN remains under-recognized and difficult to diagnose and manage. Traditional treatments have been empirical, but newer biologics show promise in reducing itch and improving skin condition. There are unmet needs in diagnosis and management, especially for adolescents and children, and more real-world data and long-term studies are necessary. The patient journey is complicated by the need for multidisciplinary care and the psychological impact of the disease, emphasizing the importance of patient education and shared decision-making in treatment plans.