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research Multifunctional Silk Fibroin Hydrogel with Antibacterial and Regenerative Properties for Accelerated Wound Healing
This study presents a multifunctional hydrogel, PBCTS@PNF, designed for advanced wound healing. The hydrogel, synthesized using PVA-borax, silk fibroin, tannic acid, and chitosan, incorporates total saponins from Panax notoginseng flower buds, offering antibacterial, antioxidant, and regenerative properties. It demonstrated high inhibition rates against E. coli (84.30%) and S. aureus (98.12%), and animal experiments showed it significantly reduced inflammation and promoted tissue regeneration, including re-epithelialization, neovascularization, and hair follicle regeneration. This hydrogel represents a promising therapeutic platform for wound management through its synergistic antibacterial, anti-inflammatory, and regenerative effects.
research Hypoxia-preconditioned ADSC exosomes encapsulated in a multifunctional dual-network hydrogel promote the healing and functional regeneration of seawater-immersed wounds
The hydrogel helps heal seawater-immersed wounds by reducing infection and inflammation.
research Borate-modified recombinant type XVII collagen microneedles loaded with IGF-1 for the treatment of androgenetic alopecia
A new microneedle treatment shows promise for better hair regrowth in androgenetic alopecia.
research Recent Advances in Biodegradable and Biocompatible Synthetic Polymers Used in Skin Wound Healing
New synthetic polymers help improve skin wound healing and can be enhanced by adding natural materials and medicines.
research Multiple crosslinked, self-healing, and shape-adaptable hydrogel laden with pain-relieving chitosan@borneol nanoparticles for infected burn wound healing
The hydrogel effectively treats infected burn wounds by reducing pain and preventing infection.
Community Join
5 / 1000+ resultscommunity Oral PTD-DBM available online, worth giving a shot?
Oral PTD-DBM was discussed as a potential hair loss treatment, but it was deemed ineffective in humans despite promising results in mice. The conversation concluded that trying it without VPA might be unwise.
community Topical VPA - Anyone experiences here?
The conversation is about using topical valproic acid (VPA) for hair loss, focusing on its application method, usage frequency, and combination with other treatments like micro-needling. No specific experiences with VPA were shared.
community I’m starting PTD-DBM and valproic acid today - anyone with experience?
The conversation is about using PTD-DBM and valproic acid for hair loss. The user is inquiring about the dosage of these treatments, noting that valproic acid is used at a 7.5% solution.
community Is anyone taking both boron and p5p to lower SHBG and Prolactin respectively? What are you experience on this?
The user is applying topical finasteride with stemoxydine for hair loss and has noticed hair thickening but no regrowth after two months. They also report high SHBG and prolactin levels and a lack of morning erections, even on low doses of medication.
community Is Vitamin B6 + Pyridoxine the same as P5P? Want to use it to reduce my Prolactin.
The user is considering using P5P to reduce high prolactin levels and is questioning if oral minoxidil could be contributing to the issue. They are also debating whether to switch from oral to topical minoxidil.