This study presents a multifunctional hydrogel, PBCTS@PNF, designed for advanced wound healing. The hydrogel, synthesized using PVA-borax, silk fibroin, tannic acid, and chitosan, incorporates total saponins from Panax notoginseng flower buds, offering antibacterial, antioxidant, and regenerative properties. It demonstrated high inhibition rates against E. coli (84.30%) and S. aureus (98.12%), and animal experiments showed it significantly reduced inflammation and promoted tissue regeneration, including re-epithelialization, neovascularization, and hair follicle regeneration. This hydrogel represents a promising therapeutic platform for wound management through its synergistic antibacterial, anti-inflammatory, and regenerative effects.
2 citations
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June 2025 in “Chemical Engineering Journal” The hydrogel helps heal seawater-immersed wounds by reducing infection and inflammation.
May 2025 in “International Journal of Biological Macromolecules” A new microneedle treatment shows promise for better hair regrowth in androgenetic alopecia.
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August 2023 in “Materials” New synthetic polymers help improve skin wound healing and can be enhanced by adding natural materials and medicines.
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December 2024 in “Theranostics” The hydrogel effectively treats infected burn wounds by reducing pain and preventing infection.
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October 2023 in “Advanced Drug Delivery Reviews” Controlling inflammation can help heal diabetic foot ulcers.
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October 2024 in “Pharmaceutics” Clindamycin-loaded nanoparticles effectively treat MRSA-infected wounds and promote healing.
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October 2016 in “Journal of The European Academy of Dermatology and Venereology” People with hair loss have worse cholesterol levels, possibly linking hair loss to heart problems.
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January 2024 in “Materials advances” Cellulose nanocrystals are promising for making effective, sustainable sensors for various uses.
June 2018 in “International journal of trend in scientific research and development” The review explains how hair products work and the science of different hair types to help improve hair care research.
December 2025 in “MEDFARM Jurnal Farmasi dan Kesehatan” Topical metformin shows promise for treating skin conditions like acne and psoriasis.
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May 2019 in “Materials Science and Engineering: C” Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.
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June 2021 in “Polymers” Photothermal hydrogels are promising for infection control and tissue repair, and combining them with other treatments could improve results and lower costs.
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January 2021 in “Journal of Clinical Medicine” Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
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February 2018 in “Bio-medical Materials and Engineering” Minoxidil inside tiny particles can deliver more drug to hair follicles, potentially improving treatment for hair loss.
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November 2009 in “Recent Patents on Drug Delivery & Formulation” Microemulsions could improve how drugs are delivered and absorbed in the body.
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December 2022 in “PÄDI Boletín Científico de Ciencias Básicas e Ingenierías del ICBI” Bioceramic and biopolymer composites are promising for advanced wound care, promoting healing and cell growth.
1 citations
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June 2025 in “Frontiers in Bioengineering and Biotechnology” Glycopeptide hydrogels are promising for tissue repair, drug delivery, and healing due to their multifunctional properties.
1 citations
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January 2022 in “Pharmaceutical Sciences Asia” Microneedles offer a painless, effective way to deliver drugs through the skin.
February 2026 in “Frontiers in Bioengineering and Biotechnology” Liposome-based systems improve skin wound healing effectively.
November 2025 in “Nanoscale Advances” Inorganic nanoparticle-based scaffolds can improve wound healing by fighting bacteria and helping tissue grow.
Polarized microscopy helps identify hair irregularities in genetic disorders.
76 citations
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February 2024 in “International Journal of Molecular Sciences” Hydrogels show promise for improving skin wound healing.
14 citations
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September 2025 in “Gels” Sodium alginate-based hydrogels are promising for medical use due to their versatility and biocompatibility.
14 citations
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April 2025 in “Nano Today” The hydrogel dressing speeds up and improves diabetic wound healing.
11 citations
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July 2024 in “Biomimetics” Injectable biomimetic gels can help heal tissues and deliver drugs but need improvements in strength and delivery.
January 2026 in “Materials Today Bio” The hydrogel speeds up diabetic wound healing by reducing inflammation and promoting skin repair.
October 2025 in “Journal of Nanobiotechnology” The hydrogel helps wounds heal better by reducing inflammation and promoting skin regeneration.
September 2025 in “Journal of Polymer Science” Functionalized bacterial cellulose can improve medical tissue engineering.